Manager Call 2016-06-15

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Minutes from the previous GO Managers Meeting can be found here.

Agenda

Identifier space in GO annotations (GAF, GPAD)

  • Address pending questions:
    • Should GO provide the digested GAF that contains only the canonical IDs in all columns (except Column 17) of GAF?
    • How should mapping of protein complex members be handled? We probably do want to have a mechanism for mapping between gene or gene-centric protein IDs and protein complexes and then automatically unfold annotations to each member of a complex using the contributes_to qualifier for MF?
    • Do we need to establish guidelines for curators who want to use more granular identifiers in AEs to make sure the IDs used correspond to the correct entity given the GO term used? How much effort should be put into this?
    • If we allow any gene or gene-centric identifier in AEs or With/From, what effects does this have on error checking?


  • For the purpose of this discussion:
    • Determine if there currently are uses cases for the more granular gene or gene product information in AEs and With/From. Consult with Val and Ruth on this. (Sent (late notice) invitation to Ruth and Val; hopefully their schedule will allow them to join).
    • Look for examples of AE usage in the literature. One possible use case mentioned in the Discussion of Gene Prioritization for Imaging Genetics Studies Using Gene Ontology and a Stratified False Discovery Rate Approach.
    • Need to check with Sandra Orchard about how protein complex mappings to gene or gcrp IDs are currently handled.

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Minutes

Attendees:

Regrets: Moni Munoz-Torres (summoned to USCIS appointment).

Agenda: Moni | Minutes: Chris

Identifier space in GO annotations (GAF, GPAD)

Begin taking notes here.