Manager Call 2020-06-17

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Agenda

  • Agenda: Laurent-Philippe
  • Minutes: David
  • Present: David, Laurent-Philippe, Kimberly, Seth, Pascale,
  • Regrets:Judy

Project plans for remainder of 2020

(Kimberly)

  • Make sure our priorities are clear for the remainder of the year
  • What are the most important things for the grant renewal?

Isoforms NOT in AmiGO/products

(Pascale, from feedback from Ruth) https://github.com/geneontology/go-site/issues/1105 Should they not be ?

I see them for mouse annotations. http://amigo.geneontology.org/amigo/search/annotation?q=*:*&fq=bioentity:%22MGI:MGI:1197518%22&sfq=document_category:%22annotation%22

Evidence code for inferred annotations

(Pascale, from an ontlogy ticket) https://github.com/geneontology/go-ontology/issues/19461

Bader gene sets

Approach to handle gene sets redundancy.

They are deriving gene sets for GO, but are using EBI and MGI for human and mouse annotations: http://baderlab.org/GeneSets#Sources.

Gene sets download: http://download.baderlab.org/EM_Genesets/current_release/Human/UniProt/

Proposals: 1) contact them to explain the benefits of fetching annotations from GOC instead of EBI/MGI instead of GOC 2) page on the go site to explain the above (differences & benefits from fetching annotations from GOC rather than a source; eg check, validations, etc) 3) some of Bader gene sets could be of interest for QC ? 4) seems like GO should be providing gene sets derived from GO BP and GO MF (unsure about the use of GO CC but would be easy to generate too)

Noctua 2.0 rollout update

  • Out on Monday and getting positive feedback
  • Some issues with rollout (dev/prod?); we will be following up

Updated GO managers page to match the Project Org chart

(Pascale)