Difference between revisions of "N-terminal and C-terminal binding"

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(Created page with "==PROBLEM== This issue concerns the terms: protein N-terminus binding ; GO:0047485 protein C-terminus binding ; GO:0008022 They are defined as binding to the N- or C-term...")
 
 
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[[Category:Binding]]
 
==PROBLEM==
 
==PROBLEM==
  

Latest revision as of 10:22, 30 June 2014

PROBLEM

This issue concerns the terms:

 protein N-terminus binding ; GO:0047485
 protein C-terminus binding ; GO:0008022


They are defined as binding to the N- or C-terminal residue of a protein, but have been used in annotation to describe binding to a domain that is in the N-terminal or C-terminal region of a protein, and this is not information that we want to capture in GO.


PROPOSAL

  • 1. Obsolete GO:0047485 and GO:0008022.
  • 2. Create new terms for protein N-terminus binding, and protein C-terminus binding.

This means that existing annotations will need to be looked at, and can be transferred to the new terms ONLY if applicable.


Related SourceForge Entries

https://sourceforge.net/tracker/?func=detail&aid=2957900&group_id=36855&atid=440764