PAINT progress report for 2015: Difference between revisions
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(Created page with "Category:Annotation '''Dec 2015''' '''Prepared and Submitted by Huaiyu Mi and Pascale Gaudet on behalf of the PAINT working group''' ===Curators=== *Marc Feuermann *Pas...") |
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*Donghui Li | *Donghui Li | ||
*Moni Munoz-Torres | *Moni Munoz-Torres | ||
===Creation of GO annotations using phylogenetic inference=== | |||
* We annotated gene families covering approximately 7200 human genes. This represents about 36% of all protein-coding genes (nearly meeting our original goal for year 4 of ????%, which assumed substantially greater resource allocation). | |||
* Of these 7200 human genes that could have potentially received additional GO annotations, the project added new annotations for about 6000 human genes (over 80%). A total of 25,000 annotations were added for these human genes (12,000 biological process, 7,000 molecular function and 6,000 cellular component annotations). This project is thus making a large impact on the computational representation of human gene function. | |||
* The project also added new annotations for an additional ~300,000 genes across 104 other genomes. | |||
* Other statistics: 2300 families have now been curated. This has resulted in the annotation of 5300 internal tree nodes, comprising 2400 molecular function annotations, 3200 biological process annotations and 2600 cellular component annotations. These annotations were propagated within the tree to annotate the 300,00 genes listed above, yielding a total of 565000 biological process annotations, 430,000 molecular function annotations and 360,000 cellular component annotations. | |||
* Updated phylogenetic trees. All gene trees were updated using the May 2014 release of the UniProt Reference Proteomes. | |||
Revision as of 17:02, 20 November 2015
Dec 2015
Prepared and Submitted by Huaiyu Mi and Pascale Gaudet on behalf of the PAINT working group
Curators
- Marc Feuermann
- Pascale Gaudet
- Karen Christie
- Huaiyu Mi
- Donghui Li
- Moni Munoz-Torres
Creation of GO annotations using phylogenetic inference
- We annotated gene families covering approximately 7200 human genes. This represents about 36% of all protein-coding genes (nearly meeting our original goal for year 4 of ????%, which assumed substantially greater resource allocation).
- Of these 7200 human genes that could have potentially received additional GO annotations, the project added new annotations for about 6000 human genes (over 80%). A total of 25,000 annotations were added for these human genes (12,000 biological process, 7,000 molecular function and 6,000 cellular component annotations). This project is thus making a large impact on the computational representation of human gene function.
- The project also added new annotations for an additional ~300,000 genes across 104 other genomes.
- Other statistics: 2300 families have now been curated. This has resulted in the annotation of 5300 internal tree nodes, comprising 2400 molecular function annotations, 3200 biological process annotations and 2600 cellular component annotations. These annotations were propagated within the tree to annotate the 300,00 genes listed above, yielding a total of 565000 biological process annotations, 430,000 molecular function annotations and 360,000 cellular component annotations.
- Updated phylogenetic trees. All gene trees were updated using the May 2014 release of the UniProt Reference Proteomes.