Panther ID:11829: Difference between revisions
Karadolinski (talk | contribs) |
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===== 1) transcription factor activity (GO:0003700) ===== | ===== 1) transcription factor activity (GO:0003700) ===== | ||
Up-propagation to common ancestor node AN0 | Up-propagation to common ancestor node AN0 (the root node) down-propagation to the following Ref Genome proteins: | ||
based on many experimental annotations, from yeast to human, that map up to the root node. | based on many experimental annotations, from yeast to human, that map up to the root node. | ||
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===== 1) nucleus (GO:0005634) ===== | ===== 1) nucleus (GO:0005634) ===== | ||
Up-propagation to common ancestor node AN0 | Up-propagation to common ancestor node AN0 (the root node) down-propagation to the following Ref Genome proteins: | ||
based on experimental annotation | based on many experimental annotations, from yeast to human, that map up to the root node. | ||
Note that no bacterial species are in this family, so erroneous annotation to 'nucleus' for bacteria is not a concern here. | |||
==== Biological Process: ==== | ==== Biological Process: ==== |
Revision as of 15:03, 20 August 2009
FOXE1/Forkhead/Forkhead box family
Summary
Molecular Function
Propagation:
1) transcription factor activity (GO:0003700)
Up-propagation to common ancestor node AN0 (the root node) down-propagation to the following Ref Genome proteins:
based on many experimental annotations, from yeast to human, that map up to the root node.
Cellular Component:
1) nucleus (GO:0005634)
Up-propagation to common ancestor node AN0 (the root node) down-propagation to the following Ref Genome proteins:
based on many experimental annotations, from yeast to human, that map up to the root node.
Note that no bacterial species are in this family, so erroneous annotation to 'nucleus' for bacteria is not a concern here.
Biological Process:
- negative regulation of interferon-gamma production (GO:0032689)
- negative regulation of interleukin-10 production (GO:0032693)
- negative regulation of interleukin-2 production (GO:0032703)
- negative regulation of interleukin-4 production (GO:0032713)
- T cell activation (GO:0042110)
- negative regulation of interleukin-2 biosynthetic process (GO:0045085)
- T cell activation (GO:0042110)
Up-propagation to common ancestor node AN175, down-propagation to the following Ref Genome proteins:
RAT_1561201
because of positive experimental annotations to
HUMAN_ENSG00000184481
MOUSE_MGI:1891915
2) negative regulation of cell proliferation (GO:0008285)
Up-propagation to common ancestor node AN27, down-propagation to the following Ref Genome proteins:
RAT_1562112
because of positive experimental annotations to
HUMAN_ENSG00000049768
MOUSE_MGI:1891436
Back to GAFs_for_trees-based_annotations