Panther ID:11829: Difference between revisions

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==== Molecular Function ====
==== Molecular Function ====


Propagation:
===== 1)  transcription factor activity (GO:0003700) DONE =====
 
===== 1)  transcription factor activity (GO:0003700) =====


Up-propagation to common ancestor node AN0 (the root node) down-propagation to the following Ref Genome proteins:
Up-propagation to common ancestor node AN0 (the root node) down-propagation to the following Ref Genome proteins:


based on many experimental annotations, from yeast to human, that map up to the root node.
based on many experimental annotations, from yeast to human, that map up to the root node.
===== 2)  protein homodimerization activity (GO:0042803) DONE  =====
Up-propagation to common ancestor node AN27, down-propagation to the following Ref Genome proteins:
RAT_1562112
because of positive experimental annotations to
HUMAN_ENSG00000049768
MOUSE_MGI:1891436


==== Cellular Component:  ====
==== Cellular Component:  ====


===== 1)  nucleus (GO:0005634) =====
===== 1)  nucleus (GO:0005634) DONE =====


Up-propagation to common ancestor node AN0 (the root node) down-propagation to the following Ref Genome proteins:
Up-propagation to common ancestor node AN0 (the root node) down-propagation to the following Ref Genome proteins:
Line 52: Line 65:


MOUSE_MGI:1891436
MOUSE_MGI:1891436
===== 3) Immune response-related annotations: =====
    * negative regulation of interferon-gamma production (GO:0032689)
    * negative regulation of interleukin-10 production (GO:0032693)
    * negative regulation of interleukin-2 production (GO:0032703)
    * negative regulation of interleukin-4 production (GO:0032713)
    * T cell activation (GO:0042110)
    * negative regulation of interleukin-2 biosynthetic process (GO:0045085)
    * T cell activation (GO:0042110)
Up-propagation to common ancestor node AN27, down-propagation to the following Ref Genome proteins:
RAT_1562112
because of positive experimental annotations to
HUMAN_ENSG00000049768
MOUSE_MGI:1891436


----
----
Back to [[GAFs_for_trees-based_annotations]]
Back to [[GAFs_for_trees-based_annotations]]

Revision as of 15:32, 20 August 2009

FOXE1/Forkhead/Forkhead box family

Summary

SourceForge Link

PPOD/OrthoMCL link

Molecular Function

1) transcription factor activity (GO:0003700) DONE

Up-propagation to common ancestor node AN0 (the root node) down-propagation to the following Ref Genome proteins:

based on many experimental annotations, from yeast to human, that map up to the root node.

2) protein homodimerization activity (GO:0042803) DONE

Up-propagation to common ancestor node AN27, down-propagation to the following Ref Genome proteins:

RAT_1562112

because of positive experimental annotations to

HUMAN_ENSG00000049768

MOUSE_MGI:1891436



Cellular Component:

1) nucleus (GO:0005634) DONE

Up-propagation to common ancestor node AN0 (the root node) down-propagation to the following Ref Genome proteins:

based on many experimental annotations, from yeast to human, that map up to the root node.

Note that no bacterial species are in this family, so erroneous annotation to 'nucleus' for bacteria is not a concern here.

Biological Process:

1) negative regulation of cell proliferation (GO:0008285)

Up-propagation to common ancestor node AN175, down-propagation to the following Ref Genome proteins:

RAT_1561201

because of positive experimental annotations to

HUMAN_ENSG00000184481

MOUSE_MGI:1891915

2) negative regulation of cell proliferation (GO:0008285)

Up-propagation to common ancestor node AN27, down-propagation to the following Ref Genome proteins:

RAT_1562112

because of positive experimental annotations to

HUMAN_ENSG00000049768

MOUSE_MGI:1891436

3) Immune response-related annotations:
   * negative regulation of interferon-gamma production (GO:0032689)
   * negative regulation of interleukin-10 production (GO:0032693)
   * negative regulation of interleukin-2 production (GO:0032703)
   * negative regulation of interleukin-4 production (GO:0032713)
   * T cell activation (GO:0042110)
   * negative regulation of interleukin-2 biosynthetic process (GO:0045085)
   * T cell activation (GO:0042110) 

Up-propagation to common ancestor node AN27, down-propagation to the following Ref Genome proteins:

RAT_1562112

because of positive experimental annotations to

HUMAN_ENSG00000049768

MOUSE_MGI:1891436



Back to GAFs_for_trees-based_annotations