Panther ID:11829: Difference between revisions
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==== Biological Process: ==== | ==== Biological Process: ==== | ||
===== 1) negative regulation of cell proliferation (GO:0008285) | ===== 1) negative regulation of cell proliferation (GO:0008285) DONE ===== | ||
Up-propagation to common ancestor node AN175, down-propagation to the following Ref Genome proteins: | Up-propagation to common ancestor node AN175, down-propagation to the following Ref Genome proteins: | ||
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MOUSE_MGI:1891915 | MOUSE_MGI:1891915 | ||
===== 2) negative regulation of cell proliferation (GO:0008285) | ===== 2) negative regulation of cell proliferation (GO:0008285) DONE ===== | ||
Up-propagation to common ancestor node AN27, down-propagation to the following Ref Genome proteins: | Up-propagation to common ancestor node AN27, down-propagation to the following Ref Genome proteins: | ||
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MOUSE_MGI:1891436 | MOUSE_MGI:1891436 | ||
===== 3) Immune response-related annotations: ===== | ===== 3) Immune response-related annotations: DONE ===== | ||
* negative regulation of interferon-gamma production (GO:0032689) | * negative regulation of interferon-gamma production (GO:0032689) | ||
Revision as of 15:34, 20 August 2009
FOXE1/Forkhead/Forkhead box family
Summary
Molecular Function
1) transcription factor activity (GO:0003700) DONE
Up-propagation to common ancestor node AN0 (the root node) down-propagation to the following Ref Genome proteins:
based on many experimental annotations, from yeast to human, that map up to the root node.
2) protein homodimerization activity (GO:0042803) DONE
Up-propagation to common ancestor node AN27, down-propagation to the following Ref Genome proteins:
RAT_1562112
because of positive experimental annotations to
HUMAN_ENSG00000049768
MOUSE_MGI:1891436
Cellular Component:
1) nucleus (GO:0005634) DONE
Up-propagation to common ancestor node AN0 (the root node) down-propagation to the following Ref Genome proteins:
based on many experimental annotations, from yeast to human, that map up to the root node.
Note that no bacterial species are in this family, so erroneous annotation to 'nucleus' for bacteria is not a concern here.
Biological Process:
1) negative regulation of cell proliferation (GO:0008285) DONE
Up-propagation to common ancestor node AN175, down-propagation to the following Ref Genome proteins:
RAT_1561201
because of positive experimental annotations to
HUMAN_ENSG00000184481
MOUSE_MGI:1891915
2) negative regulation of cell proliferation (GO:0008285) DONE
Up-propagation to common ancestor node AN27, down-propagation to the following Ref Genome proteins:
RAT_1562112
because of positive experimental annotations to
HUMAN_ENSG00000049768
MOUSE_MGI:1891436
* negative regulation of interferon-gamma production (GO:0032689) * negative regulation of interleukin-10 production (GO:0032693) * negative regulation of interleukin-2 production (GO:0032703) * negative regulation of interleukin-4 production (GO:0032713) * T cell activation (GO:0042110) * negative regulation of interleukin-2 biosynthetic process (GO:0045085) * T cell activation (GO:0042110)
Up-propagation to common ancestor node AN27, down-propagation to the following Ref Genome proteins:
RAT_1562112
because of positive experimental annotations to
HUMAN_ENSG00000049768
MOUSE_MGI:1891436
Back to GAFs_for_trees-based_annotations