Panther ID:11829

From GO Wiki
Jump to navigation Jump to search

FOXE1/Forkhead/Forkhead box family

Summary

SourceForge Link

PPOD/OrthoMCL link

Molecular Function

Propagation:

1) transcription factor activity (GO:0003700)

Up-propagation to common ancestor node AN0, the root node, down-propagation to the following Ref Genome proteins:

based on many experimental annotations, from yeast to human, that map up to the root node.

Cellular Component:

1) nucleus (GO:0005634)

Up-propagation to common ancestor node AN20, down-propagation to the following Ref Genome proteins:


RAT_1562112

HUMAN_ENSG000000128573

RAT_1559697

CHICK_769935

DANRE_ZDB-GENE-041203-2

HUMAN_ENSG00000137166

RAT_1311386

DANRE_ZDB-GENE-040426-1338

RAT_1308669

CHICK_416092

because of positive experimental annotations to

HUMAN_ENSG00000049768

MOUSE_MGI:1891436

MOUSE_MGI:1914004

HUMAN_ENSG00000114861 (annotated to nucleolus)

2) nucleus (GO:0005634)

Up-propagation to common ancestor node AN114, down-propagation to the following Ref Genome proteins:

CHICK_421769

DANRE_ZDB-GENE-990708-6

CHICK_374231

DANRE_ZDBJ-GENE-061013-59

DANRE_ENSDARG00000061549

MOUSE_MGI:1891915

CHICK_428703

HUMAN_ENSG00000204060

RAT_1595858

DANRE_ENSDARG00000024619

DANRE_ENSDARG00000055792

DANRE_ZDB-GENE-050116-1

because of positive experimental annotations to

HUMAN_ENSG00000118689

MOUSE_MGI:1890081

RAT_1309196

HUMAN_ENSG000000150907

MOUSE_MGI:1890077

RAT_620283

HUMAN_ENSG00000184481

RAT_1561201

MOUSE_MGI:2676586

Biological Process:

1) Immune response-related annotations:
  • negative regulation of interferon-gamma production (GO:0032689)
  • negative regulation of interleukin-10 production (GO:0032693)
  • negative regulation of interleukin-2 production (GO:0032703)
  • negative regulation of interleukin-4 production (GO:0032713)
  • T cell activation (GO:0042110)
  • negative regulation of interleukin-2 biosynthetic process (GO:0045085)
  • T cell activation (GO:0042110)

Up-propagation to common ancestor node AN175, down-propagation to the following Ref Genome proteins:

RAT_1561201

because of positive experimental annotations to

HUMAN_ENSG00000184481

MOUSE_MGI:1891915

2) negative regulation of cell proliferation (GO:0008285)

Up-propagation to common ancestor node AN27, down-propagation to the following Ref Genome proteins:

RAT_1562112

because of positive experimental annotations to

HUMAN_ENSG00000049768

MOUSE_MGI:1891436


Back to GAFs_for_trees-based_annotations