Panther ID:11829

FOXE1/Forkhead/Forkhead box family

Summary

SourceForge Link

PPOD/OrthoMCL link

Molecular Function

Propagation:

1) transcription factor activity (GO:0003700)

Up-propagation to common ancestor node AN0, the root node, down-propagation to the following Ref Genome proteins:

based on many experimental annotations, from yeast to human, that map up to the root node.

Cellular Component:

1) nucleus (GO:0005634)

Up-propagation to common ancestor node AN0, the root node, down-propagation to the following Ref Genome proteins:

based on experimental annotation

Biological Process:

1) Immune response-related annotations:

• negative regulation of interferon-gamma production (GO:0032689)
• negative regulation of interleukin-10 production (GO:0032693)
• negative regulation of interleukin-2 production (GO:0032703)
• negative regulation of interleukin-4 production (GO:0032713)
• T cell activation (GO:0042110)
• negative regulation of interleukin-2 biosynthetic process (GO:0045085)
• T cell activation (GO:0042110)

Up-propagation to common ancestor node AN175, down-propagation to the following Ref Genome proteins:

RAT_1561201

because of positive experimental annotations to

HUMAN_ENSG00000184481

MOUSE_MGI:1891915

2) negative regulation of cell proliferation (GO:0008285)

Up-propagation to common ancestor node AN27, down-propagation to the following Ref Genome proteins:

RAT_1562112

because of positive experimental annotations to

HUMAN_ENSG00000049768

MOUSE_MGI:1891436

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