Panther ID:22573: Difference between revisions

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See SourceForge 1893061 and 1893082.
See SourceForge 1893061 and 1893082.
General notes: The Panther family is very large, so used PPOD to look at more managable chunks of the larger Panther family:


* [[http://ppod.princeton.edu/cgi-bin/ppod.cgi/j04/Jaccard1673 PPOD Jaccard1673]]: not enough experimental annotations (only human protein UniProtKB:P00492 had exp. ann.) in this subsection of the big PANTHER family, so could not do transfer.
* [[http://ppod.princeton.edu/cgi-bin/ppod.cgi/j04/Jaccard1673 PPOD Jaccard1673]]: not enough experimental annotations (only human protein UniProtKB:P00492 had exp. ann.) in this subsection of the big PANTHER family, so could not do transfer.

Revision as of 15:32, 1 July 2009

HPRT1, hypoxanthine guanine phosphoribosyltransferase

Cross references:

See SourceForge 1893061 and 1893082.

  • [PPOD Jaccard1673]: not enough experimental annotations (only human protein UniProtKB:P00492 had exp. ann.) in this subsection of the big PANTHER family, so could not do transfer.

Molecular Function

The three cervevisiae proteins, PGM1, PGM2, and PGM3, the mouse proteins PGM1 and PGM2, and the fly protein Pgm (last one on the graph) all have experimental annotations to phosphoglucomutase activity. However, the mouse PGM5 has a NOT annotation to this activity and the human also has a NOT (but also a positive annotation(!)).

Propagation proposal: Propagate to all proteins except for the clade with the NOT annotations (mouse and human PGM5) and the three C. elegans proteins that are part of an outgroup (top of graph). Pending info from MOD curators (see below), we might propagate that NOT to the rat proteins in that clade as well.

Suggestions for MOD annotators:

  • ask about human NOT, ISO from NAS (emailed relevant curators March 18, 2009)
  • ask E. coli to possibly add experimental annotation based on PubMed: 12351653 (emailed Debby March 18, 2009)