Procedure for selection of target genes (Retired): Difference between revisions
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# Enter all ID in the [http://spreadsheets0.google.com/ccc?key=pwOksMOra5uq4vIYjPgefPw Master Table]. The Human Genome Nomenclature Committee's site is a nice source for those IDs, [http://www.genenames.org/cgi-bin/hgnc_search.pl HGNC search tool]. | # Enter all ID in the [http://spreadsheets0.google.com/ccc?key=pwOksMOra5uq4vIYjPgefPw Master Table]. The Human Genome Nomenclature Committee's site is a nice source for those IDs, [http://www.genenames.org/cgi-bin/hgnc_search.pl HGNC search tool]. | ||
# For disease genes, enter the OMIM ID of the disease or a PMID of a paper describing the gene's implication in a disease | # For disease genes, enter the OMIM ID of the disease or a PMID of a paper describing the gene's implication in a disease | ||
== Disease genes == | == Disease genes == |
Revision as of 16:46, 2 November 2007
Rotation Order
This is the list of which group is responsible for selecting curation targets for the next year:
- November 2007: Arabidopsis thaliana
- December 2007: Caenorhabditis elegans
- January 2008: Danio rerio
- February 2008: Dictyostelium discoideum
- March 2008: Drosophila melanogaster
- April 2008: Escherichia coli
- May 2008: Gallus gallus
- June 2008: Homo sapiens
- July 2008: Mus musculus
- August 2008: Rattus norvegicus
- September 2008: Saccharomyces cerevisiae
- October 2008: Schizosaccharomyces pombe
Guidelines
- Try to select related genes (same pathway, same disease)
- Check that the gene is not already done (easiest to search by UniProt ID)
- Enter all ID in the Master Table. The Human Genome Nomenclature Committee's site is a nice source for those IDs, HGNC search tool.
- For disease genes, enter the OMIM ID of the disease or a PMID of a paper describing the gene's implication in a disease
Disease genes
- OMIM Morbid Map
- RGD disease portal
- Gene Tests
- PharmGKB
- G2D
- Drosophila & human disease
- Search GoogleNews for "genes" [1]
Conserved Human-E.coli
- list of genes is in the 'Suggestions' spreadsheet (look for the "conserved Hs-Ec" sheet)
- enter the ensemble ID in YOGY
- find the UniProt ID from the YOGY summary tables
- check the 'master list' to make sure the gene has not previously been selected
Bleeding edge genes
- Recent highlighted articles in your database
- Science Daily
- Medline
- AAAS's EurekAlert
- Expasy Spotlight
- other suggestions welcome
Biochemical/signaling pathways
Try picking 5 genes form the same pathway