Procedure for selection of target genes (Retired): Difference between revisions

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[[Category:PAINT Archived]]
'''This is in progress: please fill in any information you find useful as you use this page. Also, if we change our guidelines this will be reflected here. '''
==Rotation Order==
This is the list of which group is responsible for selecting curation targets for the next year:
* November 2007: Arabidopsis thaliana
* December 2007: Caenorhabditis elegans
* January 2008: Danio rerio
* February 2008: Dictyostelium discoideum
* March 2008: Drosophila melanogaster
* April 2008: Escherichia coli
* no date Gallus gallus  (skipped!)
* Oct 2008: Homo sapiens
* TBA: Mus musculus
* TBA: Rattus norvegicus
* TBA: Saccharomyces cerevisiae
* TBA: Schizosaccharomyces pombe
== Guidelines ==
== Guidelines ==
# Try to select related genes (same pathway, same disease)
# Try to select related genes (same pathway, same disease, same gene family)
# Check that the gene is not already done (easiest to search by UniProt ID)
# Check that the gene is not already done (easiest to search by UniProt ID)
# Enter all ID in the [http://spreadsheets0.google.com/ccc?key=pwOksMOra5uq4vIYjPgefPw Master Table]
# Enter all ID in the [http://spreadsheets0.google.com/ccc?key=pwOksMOra5uq4vIYjPgefPw Master Table]. The Human Genome Nomenclature Committee's site is a nice source for those IDs, [http://www.genenames.org/cgi-bin/hgnc_search.pl HGNC search tool]. '''Please separate all names by commas and remove any non-required character (tabs, line feed, etc)'''
# For disease genes, enter the OMIM ID of the disease or a PMID of a paper describing the gene's implication in a disease
# For disease genes, enter the OMIM ID of the disease or a PMID of a paper describing the gene's implication in a disease


== Disease genes ==
== Disease genes ==
* [http://www.ncbi.nlm.nih.gov/Omim/getmorbid.cgi OMIM Morbid Map]
* [http://www.ncbi.nlm.nih.gov/Omim/getmorbid.cgi OMIM Morbid Map]
(also in the 'Suggestion' google spreadsheet; please mark those you select)
* [http://rgd.mcw.edu/dportal/ RGD disease portal]
* [http://rgd.mcw.edu/dportal/ RGD disease portal]
* [http://www.genetests.org Gene Tests]
* [http://www.genetests.org Gene Tests]
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* [http://www.ogic.ca/projects/g2d_2/ G2D]
* [http://www.ogic.ca/projects/g2d_2/ G2D]
* [http://superfly.ucsd.edu/homophila/ Drosophila & human disease]
* [http://superfly.ucsd.edu/homophila/ Drosophila & human disease]
* Search GoogleNews for "genes" [http://news.google.com/news?hl=en&ned=us&q=genes&btnG=Search+News]


== Conserved Human-E.coli ==
== Conserved Human-E.coli ==
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* [http://www.sciencedaily.com/news/health_medicine/genes/display=headlines Science Daily]
* [http://www.sciencedaily.com/news/health_medicine/genes/display=headlines Science Daily]
* [http://www.nlm.nih.gov/medlineplus/newsbydate.html Medline]
* [http://www.nlm.nih.gov/medlineplus/newsbydate.html Medline]
* [http://www.eurekalert.org/bysubject/biology.php AAAS's EurekAlert]
* [http://expasy.org/spotlight/snapshot/index.shtml Expasy Spotlight]
* [http://expasy.org/spotlight/snapshot/index.shtml Expasy Spotlight]
* other suggestions welcome
* other suggestions welcome

Latest revision as of 11:32, 12 April 2019

This is in progress: please fill in any information you find useful as you use this page. Also, if we change our guidelines this will be reflected here.

Rotation Order

This is the list of which group is responsible for selecting curation targets for the next year:

  • November 2007: Arabidopsis thaliana
  • December 2007: Caenorhabditis elegans
  • January 2008: Danio rerio
  • February 2008: Dictyostelium discoideum
  • March 2008: Drosophila melanogaster
  • April 2008: Escherichia coli
  • no date Gallus gallus (skipped!)
  • Oct 2008: Homo sapiens
  • TBA: Mus musculus
  • TBA: Rattus norvegicus
  • TBA: Saccharomyces cerevisiae
  • TBA: Schizosaccharomyces pombe

Guidelines

  1. Try to select related genes (same pathway, same disease, same gene family)
  2. Check that the gene is not already done (easiest to search by UniProt ID)
  3. Enter all ID in the Master Table. The Human Genome Nomenclature Committee's site is a nice source for those IDs, HGNC search tool. Please separate all names by commas and remove any non-required character (tabs, line feed, etc)
  4. For disease genes, enter the OMIM ID of the disease or a PMID of a paper describing the gene's implication in a disease

Disease genes

(also in the 'Suggestion' google spreadsheet; please mark those you select)

Conserved Human-E.coli

  • list of genes is in the 'Suggestions' spreadsheet (look for the "conserved Hs-Ec" sheet)
  • enter the ensemble ID in YOGY
  • find the UniProt ID from the YOGY summary tables
  • check the 'master list' to make sure the gene has not previously been selected

Bleeding edge genes

Biochemical/signaling pathways

Try picking 5 genes form the same pathway