QCQA next call: Difference between revisions

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http://wiki.geneontology.org/index.php/QCQA_call_2018-08-21
=Preparing for GOC meeting =
 
=Annotation redundancy - non-experimental annotations=
**Can we come up with a proposal for the Montreal meeting?
**http://wiki.geneontology.org/index.php/2018_Montreal_GOC_Meeting_Agenda#Handling_redundant_information
 
==Discussion: Annotation redundancy - non-experimental annotations==
* We need to define what constitutes a redundant information, WRT to sources, evidences and references
* There is a ticket that explains the strategy that will be taken for this: see https://github.com/geneontology/amigo/issues/43 and https://github.com/geneontology/amigo/issues/440
* '''AI: Rules for flagging redundant annotations need to be documented - Chris'''
 
==New error reports - status==


=New error reports=
http://snapshot.geneontology.org/reports/gorule-report.html
http://snapshot.geneontology.org/reports/gorule-report.html
https://github.com/geneontology/go-site/issues/709
https://github.com/geneontology/go-site/issues/709
* Discuss - feedback and priorities


= github tickets =
== Ontology tracker ==
*[https://github.com/geneontology/go-ontology/issues/16108 GO:0071554 cell wall organization and biogenesis taxon restrictions #16108]


=How to blacklist papers=
=How to blacklist papers=
This would include retracted papers and predatory journals
Pascale
https://github.com/geneontology/go-annotation/issues/2029
* List/form template of excluded papers or combinations of PMID/Gene/GO
 
= New QC check? =
*Check for genes annotated to an MF as well as BP 'regulation of that same MF'?
*Would that ever make sense?
*See https://www.uniprot.org/uniprot/Q7Z7L7 as an example


= Reported from the previous meeting =
= Update: Unmaintained annotation sets=
 
* Should Taxon checks be a hard check:  
https://github.com/geneontology/go-site/issues/660
https://github.com/geneontology/go-site/issues/758
 
* Unmaintained annotation sets:
https://github.com/geneontology/go-annotation/issues/1724#issuecomment-390136730
https://github.com/geneontology/go-annotation/issues/1724#issuecomment-390136730
* '''AI: check status with Tony - Unmaintained annotation sets'''


TIGR, JCVI, PAMGO ISS annotations: Michelle:  
TIGR, JCVI, PAMGO ISS annotations: Michelle:  
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I think we (and hopefully PAMGO) were pretty good about using the GO_REFs to indicate whether it was HMM or pairwise. The problem with replacing our HMM annotations with InterPro2GO mappings is that we made much more specific annotations based on HMMs than what the InterPro mappings often do. I'd hate to lose those but I understand your desire to keep the annotations current.
I think we (and hopefully PAMGO) were pretty good about using the GO_REFs to indicate whether it was HMM or pairwise. The problem with replacing our HMM annotations with InterPro2GO mappings is that we made much more specific annotations based on HMMs than what the InterPro mappings often do. I'd hate to lose those but I understand your desire to keep the annotations current.


* SPKW hierarchy - at odds with transitivity as found in GO ontology?
**https://github.com/geneontology/go-annotation/issues/2036
**emailed Chris, Seth about help with querying the GO database for non-redundant SPKW-based annotations (2018-08-16)


*Annotation redundancy - non-experimental annotations
= Reported from the previous meeting =
**Can we come up with a proposal for the Montreal meeting?
**http://wiki.geneontology.org/index.php/2018_Montreal_GOC_Meeting_Agenda#Handling_redundant_information
** see https://github.com/geneontology/amigo/issues/43 and https://github.com/geneontology/amigo/issues/440


* GO-CAM QC plan
* GO-CAM QC plan
** including SynGO, > 90 % of the production models
** including SynGO, > 90 % of the production models
=To revisit later=
==SPKW hierarchy - at odds with transitivity as found in GO ontology?==
**https://github.com/geneontology/go-annotation/issues/2036
**emailed Chris, Seth about help with querying the GO database for non-redundant SPKW-based annotations (2018-08-16)
** Kimberly: WB looking into the information added by SPKW in WormBase. From that evaluation we can perhaps decide whether we want to keep them. 




[[Category:Quality Control]]
[[Category:Quality Control]]

Revision as of 11:38, 2 October 2018

Preparing for GOC meeting

Annotation redundancy - non-experimental annotations

Discussion: Annotation redundancy - non-experimental annotations

New error reports - status

http://snapshot.geneontology.org/reports/gorule-report.html https://github.com/geneontology/go-site/issues/709


How to blacklist papers

Pascale

  • List/form template of excluded papers or combinations of PMID/Gene/GO

Update: Unmaintained annotation sets

https://github.com/geneontology/go-annotation/issues/1724#issuecomment-390136730

  • AI: check status with Tony - Unmaintained annotation sets

TIGR, JCVI, PAMGO ISS annotations: Michelle: The ISS annotations from at least TIGR (and should be also JCVI and PAMGO) were all manual. They were either matches to HMMs or based on pairwise alignments. We used IEA for any annotations that were automatic from our pipeline and not reviewed. I assume JCVI continued that process after I left - at least until they stopped using their pipeline and shifted completely to using the NCBI PGAP tool (prokaryotic genome annotation pipeline). I think we (and hopefully PAMGO) were pretty good about using the GO_REFs to indicate whether it was HMM or pairwise. The problem with replacing our HMM annotations with InterPro2GO mappings is that we made much more specific annotations based on HMMs than what the InterPro mappings often do. I'd hate to lose those but I understand your desire to keep the annotations current.


Reported from the previous meeting

  • GO-CAM QC plan
    • including SynGO, > 90 % of the production models


To revisit later

SPKW hierarchy - at odds with transitivity as found in GO ontology?

    • https://github.com/geneontology/go-annotation/issues/2036
    • emailed Chris, Seth about help with querying the GO database for non-redundant SPKW-based annotations (2018-08-16)
    • Kimberly: WB looking into the information added by SPKW in WormBase. From that evaluation we can perhaps decide whether we want to keep them.