RefGenome11Sept07 Phone Conference (Archived)

Tuesday September 11, 2007, 1 PM CDT (11 AM PDT, 7 PM BST)

Present

• Petra Fey (dictyBase)
• Ruth Lovering (HGNC)
• Judy Blake (MGI)
• David Hill (MGI)
• Harold Drabkin (MGI)
• Emily Dimmer (GOA)
• Kimberly Van Auken (wormbase)
• Donghui Li(TAIR)
• Susan Tweedie (flybase)
• Val Wood (Sanger- pombe)
• Victoria Petri (RGD)
• Chris Mungall (NCBO)
• Suzi Lewis
• Rex Chisholm (dictyBAse)
• Doug Howe (ZFIN)
• ??? (SGD)

Discuss meeting agenda

Judy-suggested restructure of the Ref Gen meeting agenda to accommodate a conference call with other PIs involved in the genome Resource Informatics Network (GRIN).

Proposed Agenda Update: 26th AM - Orthology discussion (moderated by Kara Dolinski) 26th Noonish - Conference call with the GRIN PIs to discuss conservation of effort, orthology sets, sharing data. 26th PM - Discussion of:

  priorities (moderated by Rex and Pascale)

  methods (moderated by Suzi, Judy expounds)

  metrics (moderated by Ruth)
  tools (Moderated by Chris with assist from Mary) 

Review Action Items

We need to have some documentation ready for the meeting

1. Judy, Petra, Karen, DongHui and Kimberley summarize how the different Tools for identifying orthologs work, algorithm explanations, order of preference and pitfalls in identifying orthologs

  Would it also be helpful to have groups present 1-2 of their more difficult ortholog assignment cases at the Princeton
  meeting so that we can attempt to draw up some guidelines for how to handle these cases?

  I'd be willing to collect and collate these before the meeting.  

                                                                  --Kimberly

1. Annotation consistency/ quality control: Rex and Pascale will send all the curators on the RG mailing list a list of genes to verify; we'll see how it goes and discuss next time. See example ATPAF2
2. Continue discussion on Outreach: publicizing the project and developing a web presence (lead by Susan and Rex)
3. Continue discussion on Metrics: breath and depth of annotations (Rex, Judy, Ruth)

Curation Targets

• If all goes according to plan, those should have been selected from the RGD neurological disease list.
• Any comments?

Next meeting

Tuesday October 16, 10 AM CDT (8 AM PDT, 4 PM BST)