RefGenome9Oct07 Phone Conference (Archived)
Tuesday October 9, 2007, 10 AM CDT (8 AM PDT, 4 PM BST)
Present
- Judy Blake (MGI)
- David Hill (MGI)
- Harold Drabkin (MGI)
- Mary Dolan (MGI, software group)
- Emily Dimmer (GOA)
- Rachel Huntley (GOA)
- Donghui Li(TAIR)
- Susan Tweedie (flybase)
- Victoria Petri (RGD)
- Rex Chisholm (dictyBase)
- Pascale Gaudet (dictyBase)
- Petra Fey (dictyBase)
- Doug Howe (ZFIN)
- Stacia Engel (SGD)
- Ruth Lovering (university College London)
Curation Targets
- Comments on last list with the four groups : disease, conserved&unannotated; 'bleeding edge'; biochemical/signaling pathways
- Comments on rotation for selecting targets- see Procedure_for_selection_of_target_genes
Action items
[ACTION ITEM] (Jim): Provide the set of conserved genes found by InParanoid that are conserved in all 12 species (660 or so); we might want to prioritize this list by ascending order of number of annotations to target unannotated genes (who can do that?) [DONE] 'Suggestions' spreadsheet (look for the "conserved Hs-Ec" sheet)
[ACTION ITEM] (Val): Provide the list of 207 genes conserved between pombe and human with no annotation/information
[ACTION ITEM] (Ruth): send the HGNC list of genes with few annotations (potential 'bleeding edge' genes)
Reference Genome Meeting minutes available
Please read and edit if necessary Reference_Genome_minutes
We'll go over action items from the meeting.
[ACTION ITEM]: For orthology determination: Suzi and Karen E will generate a page where all sequences will be available
[ACTION ITEM]: (Judy) contact/meet with people who have made tools for orthology determination on behalf of the GOC to see if they can help us (that possibly includes re-running the analyses using the most recent set of sequences and proper IDs)
- Compara:
- Homologene:
- TreeFam
- in paranoid
- others?
[ACTION ITEM]: Kara, Stacia: run the P-POD over the full ref genomes set? analysis on the ref genome data set. Need computational pipeline with existing resources. Currently takes 3 weeks to do 8 species all v all. Goal was set for February 2008 to include all ref genome sets.
[ACTION ITEM]: (developers/software group): consider the potential impact of annotating to different forms of the gene (alternatively spliced, processed, etc).
[ACTION ITEM]: (all): provide the method you use for capturing the exact gene product being annotated.
[ACTION ITEM]? (Chris, Mike): Provide Ref genome reports on a regular basis?
[ACTION ITEM] (Pascale, ): Provide guidelines for filling the google spreadsheet (IDs, where to put notes, etc)
[ACTION ITEM]: generate reports for potential misannotations (ND annotations for completed genes, etc)
[ACTION ITEM]: generate list of terms that often have incorrect annotations to check for consistent use of the term
[ACTION ITEM] (Tanya Berardini, Emily Dimmer, Pascale Gaudet, David Hill, Chris Mungall, Kimberly Van Auken): Write up recommendations for usage of ISS, IEA, IC: Report by next meeting???
[ACTION ITEM] Amelia (web page), Susan, Rex, Petra (content), work on web presence : Report by next meeting???
[ACTION ITEM] (Judy Blake) Contact NCBI/NLM/OMIM to link to reference genome genes
Next meeting
Tuesday November 13, 1 PM CDT (11 AM PDT, 7 PM BST)