Signaling Workshop February 2010: Difference between revisions
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Return to [[Main_Page|GOC Main Page]] | Return to [[Main_Page|GOC Main Page]] | ||
Return to [[Signaling | Return to Signaling Main Page [[http://wiki.geneontology.org/index.php/Signaling]] | ||
Please suggest agenda items, relevant papers and other information relating to signaling GO terms that you would like discussed at this workshop. | Please suggest agenda items, relevant papers and other information relating to signaling GO terms that you would like discussed at this workshop. | ||
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{| class="wikitable" border="1" | {| class="wikitable" border="1" | ||
|- | |- | ||
! GO | ! GO Annotators | ||
! GO Editors | ! GO Editors | ||
! | ! Signaling Experts | ||
|- | |- | ||
| Dr Ruth Lovering (BHF-UCL)<br/>Dr Varsha Khodiyar (BHF-UCL)<br/>Dr Sandra Orchard (Intact)<br/>Dr Peter D'Eustachio (Reactome) <br/>Dr Rachael Huntley(GOA) <br/>Dr Val Wood (PombeBase)<br/>Dr Alex Diehl (MGI) (TBC) | | Dr Ruth Lovering (BHF-UCL)<br/>Dr Varsha Khodiyar (BHF-UCL)<br/>Dr Sandra Orchard (Intact)<br/>Dr Peter D'Eustachio (Reactome) <br/>Dr Rachael Huntley(GOA) <br/>Dr Val Wood (PombeBase)<br/>Dr Alex Diehl (MGI) (TBC) | ||
| Dr Rebecca Foulger (GO Editorial)<br/>Dr Midori Harris (GO Editorial) | | Dr Rebecca Foulger (GO Editorial)<br/>Dr Midori Harris (GO Editorial) | ||
| Dr Andrea Townsend-Nicholson (UCL) | | Dr Andrea Townsend-Nicholson (UCL)<br/>Dr Andrew Winter (Univeristy Edinburgh)<br/>Dr Andrew Chatr-aryamontri (University Edinburgh) | ||
|} | |} | ||
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== | == Relevant papers and other resources == | ||
Biochemistry of Signal Tranduction and Regulation. Gerhard Krauss. ISBN:3-527-29241-1 | |||
== Topics == | |||
*<font color="blue">How the signaling node should be split</font color> | |||
**cellular vs tissue vs organismal? | |||
**pathway vs process? | |||
*<font color="purple">Defining and placing:</font color> | |||
**signal transduction | |||
**signal transmission | |||
**signaling pathway | |||
*<font color="green">Connecting the networks</font color> | |||
**How to connect the cell surface receptors with the intracellular 'modules' they signal through | |||
*<font color="red">Dealing with ligand-receptor signaling that is not 1:1</font color> | |||
*<font color="magenta">What is a signal transducer?</font color> | |||
**adaptor proteins? | |||
**receptors? | |||
**ligands? | |||
= | *<font color="burgundy">Should ligand-gated ion channels be given receptor parents?</font color> | ||
== SourceForge Signaling Items == | == SourceForge Signaling Items == | ||
receptors and HAS_PART: http://sourceforge.net/tracker/?func=detail&aid=3103037&group_id=36855&atid=440764 | |||
receptor signaling proteins: http://sourceforge.net/tracker/?func=detail&aid=3101487&group_id=36855&atid=440764 | |||
purigenic receptors: http://sourceforge.net/tracker/?func=detail&aid=3088079&group_id=36855&atid=440764 | |||
MAPKKK cascade: http://sourceforge.net/tracker/?func=detail&aid=3085150&group_id=36855&atid=440764 | |||
Calcium-mediated signaling; http://sourceforge.net/tracker/?func=detail&aid=3077377&group_id=36855&atid=440764 | |||
morphogen: http://sourceforge.net/tracker/?func=detail&aid=3026415&group_id=36855&atid=440764 | |||
norrin signaling (example of non 1:1 receptor:ligand signaling) : http://sourceforge.net/tracker/?func=detail&aid=3041964&group_id=36855&atid=440764 | |||
hormone and hormone receptor signaling: http://sourceforge.net/tracker/?func=detail&aid=2974691&group_id=36855&atid=440764 | |||
Connecting up receptors and intracellular modules: | |||
wnt signaling via hippo cascade: http://sourceforge.net/tracker/?func=detail&aid=3032564&group_id=36855&atid=440764 | |||
wnt signaling via JNK cascade: http://sourceforge.net/tracker/?func=detail&aid=3023417&group_id=36855&atid=440764 | |||
== Minutes == | |||
Revision as of 10:09, 5 November 2010
Return to GOC Main Page
Return to Signaling Main Page [[1]]
Please suggest agenda items, relevant papers and other information relating to signaling GO terms that you would like discussed at this workshop.
Participants
GO Annotators | GO Editors | Signaling Experts |
---|---|---|
Dr Ruth Lovering (BHF-UCL) Dr Varsha Khodiyar (BHF-UCL) Dr Sandra Orchard (Intact) Dr Peter D'Eustachio (Reactome) Dr Rachael Huntley(GOA) Dr Val Wood (PombeBase) Dr Alex Diehl (MGI) (TBC) |
Dr Rebecca Foulger (GO Editorial) Dr Midori Harris (GO Editorial) |
Dr Andrea Townsend-Nicholson (UCL) Dr Andrew Winter (Univeristy Edinburgh) Dr Andrew Chatr-aryamontri (University Edinburgh) |
Where and When
Date: Wednesday 16th February and Thursday 17th February, 2011.
Where: EMBL-EBI.
Wednesday: A2-33 Thursday: Courtyard room
- Travel instructions to the EBI, The Wellcome Trust Genome Campus, Hinxton, Cambridgeshire CB10 1SD [2]
- Please let EBI reception know you have arrived, and Rebecca will come and meet you.
Programme
Wednesday 16th February
9:15am | Tea and Coffee | |
9:30am | Welcome and introduction | Rebecca |
9:35am | Introduction to GO | Rebecca |
9:50am | ||
11am | Coffee break | |
11:45am | ||
12:30pm | Lunch @ on-site campus restaurant | |
2pm | ||
3:00 pm | Coffee break | |
5pm | Close |
Thrusday 17th February
9:15am | Tea and Coffee | |
9:30am | Recap of decisions made on Day 1. | Rebecca |
10am | ||
11am | Coffee break | |
12:30pm | Lunch @ on-site campus restaurant | |
3:00 pm | Close |
Relevant papers and other resources
Biochemistry of Signal Tranduction and Regulation. Gerhard Krauss. ISBN:3-527-29241-1
Topics
- How the signaling node should be split
- cellular vs tissue vs organismal?
- pathway vs process?
- Defining and placing:
- signal transduction
- signal transmission
- signaling pathway
- Connecting the networks
- How to connect the cell surface receptors with the intracellular 'modules' they signal through
- Dealing with ligand-receptor signaling that is not 1:1
- What is a signal transducer?
- adaptor proteins?
- receptors?
- ligands?
- Should ligand-gated ion channels be given receptor parents?
SourceForge Signaling Items
receptors and HAS_PART: http://sourceforge.net/tracker/?func=detail&aid=3103037&group_id=36855&atid=440764
receptor signaling proteins: http://sourceforge.net/tracker/?func=detail&aid=3101487&group_id=36855&atid=440764
purigenic receptors: http://sourceforge.net/tracker/?func=detail&aid=3088079&group_id=36855&atid=440764
MAPKKK cascade: http://sourceforge.net/tracker/?func=detail&aid=3085150&group_id=36855&atid=440764
Calcium-mediated signaling; http://sourceforge.net/tracker/?func=detail&aid=3077377&group_id=36855&atid=440764
morphogen: http://sourceforge.net/tracker/?func=detail&aid=3026415&group_id=36855&atid=440764
norrin signaling (example of non 1:1 receptor:ligand signaling) : http://sourceforge.net/tracker/?func=detail&aid=3041964&group_id=36855&atid=440764
hormone and hormone receptor signaling: http://sourceforge.net/tracker/?func=detail&aid=2974691&group_id=36855&atid=440764
Connecting up receptors and intracellular modules:
wnt signaling via hippo cascade: http://sourceforge.net/tracker/?func=detail&aid=3032564&group_id=36855&atid=440764
wnt signaling via JNK cascade: http://sourceforge.net/tracker/?func=detail&aid=3023417&group_id=36855&atid=440764
Minutes
Notes
Definition Adjustments:
Obsoleted Terms:
Moved Terms:
New Terms: