Signaling nomenclature: Difference between revisions
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(Created page with " ==SIGNALING NOMENCLATURE== The diagram below shows how the signaling terms are linked to the 'response to' terms, and what the main signaling terms encompass: [[File:Signalin...") |
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==SIGNALING NOMENCLATURE== | ==SIGNALING NOMENCLATURE== | ||
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The diagram below shows how the signaling terms are linked to the 'response to' terms, and what the main signaling terms encompass: | The diagram below shows how the signaling terms are linked to the 'response to' terms, and what the main signaling terms encompass: | ||
[[ | [[Media:Signaling_nomenclature.pdf]] | ||
'''RESPONSE TO..''' | '''<font color="navy">RESPONSE TO..</font color>''' | ||
*Includes both the signaling pathway AND the downstream cellular process (e.g. transcription). | *Includes both the signaling pathway AND the downstream cellular process (e.g. transcription). | ||
*Note that ligand are included in the response. | *Note that ligand are included in the response. | ||
'''SIGNALING''' | |||
'''<font color="navy">SIGNALING</font color>''' | |||
*Begins with an active signal. Includes transport of the active signal from the signaling to the receiving cell AND signal transduction in the receiving cell. | *Begins with an active signal. Includes transport of the active signal from the signaling to the receiving cell AND signal transduction in the receiving cell. | ||
'''SIGNAL TRANSDUCTION''' | |||
'''<font color="navy">SIGNAL TRANSDUCTION</font color>''' | |||
*Limited to events IN THE RECEIVING CELL. Begins with receptor-ligand interaction (E.g. binding) and ends with REGULATION of a downstream cellular process. | *Limited to events IN THE RECEIVING CELL. Begins with receptor-ligand interaction (E.g. binding) and ends with REGULATION of a downstream cellular process. | ||
*Note that ligands are included in signal transduction. Ligands are signals and are not signal transducers. | *Note that ligands are included in signal transduction. Ligands are signals and are not signal transducers. | ||
'''SIGNALING PATHWAY''' | |||
'''<font color="navy">SIGNALING PATHWAY</font color>''' | |||
*Specific instances of signal transduction, named after the receptor or the ligand (or both). | *Specific instances of signal transduction, named after the receptor or the ligand (or both). | ||
*Specific transcription factors are INCLUDED in the signaling pathway because they REGULATE transcription. | *Specific transcription factors are INCLUDED in the signaling pathway because they REGULATE transcription. | ||
*RNA polymerase and other basal transcription factors are NOT included in the signaling pathway because they are involved in transcription itself. | *RNA polymerase and other basal transcription factors are NOT included in the signaling pathway because they are involved in transcription itself. | ||
'''INTRACELLULAR SIGNAL TRANSDUCTION''' | |||
'''<font color="navy">INTRACELLULAR SIGNAL TRANSDUCTION</font color>''' | |||
*Begins with a receptor signaling to downstream intracellular components. | *Begins with a receptor signaling to downstream intracellular components. | ||
*Includes signaling cascades | *Includes signaling cascades | ||
'''SIGNALING CASCADE''' | |||
'''<font color="navy">SIGNALING CASCADE</font color>''' | |||
*A group of INTRACELLULAR signal transducers. | *A group of INTRACELLULAR signal transducers. | ||
*Also called a signaling cassette/module. | *Also called a signaling cassette/module. | ||
[[Category:Ontology]] | |||
Revision as of 08:05, 4 October 2011
Return to GOC Main Page
SIGNALING NOMENCLATURE
The diagram below shows how the signaling terms are linked to the 'response to' terms, and what the main signaling terms encompass:
Media:Signaling_nomenclature.pdf
RESPONSE TO..
- Includes both the signaling pathway AND the downstream cellular process (e.g. transcription).
- Note that ligand are included in the response.
SIGNALING
- Begins with an active signal. Includes transport of the active signal from the signaling to the receiving cell AND signal transduction in the receiving cell.
SIGNAL TRANSDUCTION
- Limited to events IN THE RECEIVING CELL. Begins with receptor-ligand interaction (E.g. binding) and ends with REGULATION of a downstream cellular process.
- Note that ligands are included in signal transduction. Ligands are signals and are not signal transducers.
SIGNALING PATHWAY
- Specific instances of signal transduction, named after the receptor or the ligand (or both).
- Specific transcription factors are INCLUDED in the signaling pathway because they REGULATE transcription.
- RNA polymerase and other basal transcription factors are NOT included in the signaling pathway because they are involved in transcription itself.
INTRACELLULAR SIGNAL TRANSDUCTION
- Begins with a receptor signaling to downstream intracellular components.
- Includes signaling cascades
SIGNALING CASCADE
- A group of INTRACELLULAR signal transducers.
- Also called a signaling cassette/module.