Signaling regulation terms
April 20th 2010
Created 3 new terms:
- regulation of signaling pathway ; GO:0035466 (NEW)
- negative regulation of signaling pathway ; GO:0035467 (NEW)
- positive regulation of signaling pathway ; GO:0035468 (NEW)
And moved the regulation of x signaling pathway terms to be under these new terms.
Kept the existing reg of signal transduction terms:
- regulation of signal transduction ; GO:0009966
- negative regulation of signal transduction ; GO:0009968
- positive regulation of signal transduction ; GO:0009967
And left the following terms under the signal transduction part of the tree:
- modulation by symbiont of host salicylic acid-mediated defense response ; GO:0052089
- modulation of signal transduction pathway in other organism during symbiotic interaction ; GO:0052250
- regulation of mitotic cell cycle spindle assembly checkpoint ; GO:0090266
- regulation of signal transduction in response to host ; GO:0075147
- regulation of signal transduction involved in conjugation with cellular fusion ; GO:0060238
- regulation of two-component signal transduction system (phosphorelay) ; GO:0070297
(and the positive and negative children)
It's still not perfect, because in the signaling pathway part of the graph we have a mixture of terms:
- receptor signaling
- ligand signaling
- signaling 'cascades/signal transduction' downstream of the cell surface receptor.
so some terms may need to be re-given the signal transduction parentage and the regulation of signal transduction parentage.