Signaling to do list: Difference between revisions

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(Created page with 'Project from Chris: <pre> >> (4) 'signal transmission' is defined as: >> "The process whereby a signal is released and/or conveyed from one location to another. The process ter…')
 
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>> (4) 'signal transmission' is defined as:
>> (4) 'signal transmission' is defined as:
>> "The process whereby a signal is released and/or conveyed from one location to another. The process terminates at the end of the sub-process of signal transduction, when the function of the cell has been altered as a consequence of receipt of the signal."
>> "The process whereby a signal is released and/or conveyed from  
>> So, the definition says that signal transduction is a sub-process of signal transmission.  This implies that signal transduction is part_of signal transmission.  Yet 'signal transduction' is an is_a child of signal transmission.  Which is correct?
one location to another. The process terminates at the end of the  
sub-process of signal transduction, when the function of the cell  
has been altered as a consequence of receipt of the signal."
>> So, the definition says that signal transduction is a sub-process
of signal transmission.  This implies that signal transduction is  
part_of signal transmission.  Yet 'signal transduction' is an is_a  
child of signal transmission.  Which is correct?
>
>
> I think they are both correct. I am going to leave the relationship as is_a. We could follow this up in a separate thread if you'd like to discuss it.
> I think they are both correct. I am going to leave the relationship
as is_a. We could follow this up in a separate thread if you'd like to discuss it.


This is a bit worrying.
This is a bit worrying.


What I would really appreciate is a simple diagram showing the flow of time on the x axis, with the processes arranged according to the allen interval relations (http://www.ics.uci.edu/~alspaugh/cls/shr/allen.html ). Looking at signaling3.obo doesn't really tell me the changes.
What I would really appreciate is a simple diagram showing the flow  
of time on the x axis, with the processes arranged according to the  
allen interval relations (http://www.ics.uci.edu/~alspaugh/cls/shr/allen.html ).
Looking at signaling3.obo doesn't really tell me the changes.


for example, is a receptor binding pathway always immediately preceded by receptor binding? (Reactome doesn't appear to be consistent here)
for example, is a receptor binding pathway always immediately preceded  
by receptor binding? (Reactome doesn't appear to be consistent here)


I think we should get the logical definition template correct first. I have set up a file biological_process_xp_signaling.obo
I think we should get the logical definition template correct first.  
I have set up a file biological_process_xp_signaling.obo


I used starts_with, which implies part_of, but I think this should really be initiated_by  
I used starts_with, which implies part_of, but I think this should  
really be initiated_by  


</pre>
</pre>

Revision as of 05:56, 1 February 2010

Project from Chris:


>> (4) 'signal transmission' is defined as:
>> "The process whereby a signal is released and/or conveyed from 
one location to another. The process terminates at the end of the 
sub-process of signal transduction, when the function of the cell 
has been altered as a consequence of receipt of the signal."
>> So, the definition says that signal transduction is a sub-process
 of signal transmission.  This implies that signal transduction is 
part_of signal transmission.  Yet 'signal transduction' is an is_a 
child of signal transmission.  Which is correct?
>
> I think they are both correct. I am going to leave the relationship
 as is_a. We could follow this up in a separate thread if you'd like to discuss it.

This is a bit worrying.

What I would really appreciate is a simple diagram showing the flow 
of time on the x axis, with the processes arranged according to the 
allen interval relations (http://www.ics.uci.edu/~alspaugh/cls/shr/allen.html ).
 Looking at signaling3.obo doesn't really tell me the changes.

for example, is a receptor binding pathway always immediately preceded 
by receptor binding? (Reactome doesn't appear to be consistent here)

I think we should get the logical definition template correct first. 
I have set up a file biological_process_xp_signaling.obo

I used starts_with, which implies part_of, but I think this should 
really be initiated_by