Signalling Workshop Agenda

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• Ruth (UCL) will chair the morning session; Kimberly (WB) will chair the afternoon session

Time	Item	Minutes
9:00am - 9:15am	Opening Remarks - Ruth (UCl)	Val (PomBase)
9:20am - 9:45am	Summary of Approach and Project Organization - David H. (MGI) and Kimberly (WB)	Val (PomBase)
9:50am - 10:50am	Canonical Wnt Signaling - Helen (FB) and Kimberly (WB)	Val (PomBase)
11:00am - 11:30am	BREAK	na
11:30am - 12:30pm	MAPK Signaling - David H. (MGI) and Sabrina (ZFIN)
12:30pm - 1:30pm	LUNCH	na
1:30pm - 2:30pm	GPCR Signaling - Pascale (SIB) and Petra (dictyBase)
2:30pm - 3:00pm	JAK/STAT Signaling - Giulia (FB) and Ruth (UCL)
3:00pm - 3:30pm	Ca2+ Signaling involved in Mammalian Fertilization - Penelope (UniProt)
3:30pm - 4:00pm	BREAK	na
4:00pm - 5:00pm	Discussion

Proposed topics for discussion (suggested prior to meeting; please see agenda for actual topics and schedule)

Proposer (and group)	Signaling pathway	Reference	What this pathway offers	link to uploaded figures and noctua model
Judy (MGI)	General information	[http://www.cellsignallingbiology.org/csb/002/002.pdf cell signaling pathways	useful overview of lots of different types of pathways
Val (PomBase)	TOR signalling
Ruth (UCL)	Gastrin signaling	PMID:26205660	Multiple intracellular signaling pathways converge to regulate transcription (see Fig 2) Fig2B nicely groups different 'parts' of the pathway. Also brings to discussion annotation of entities responsible for release of the ligand.	impossible to get this modelled in GO-CAM before October
Ruth (UCL)	Apoptosis	Apoptosis working group	this has already been worked on in GO and guidelines established, need to consider aligning to these	Apoptosis curation manual

Other databases with signalling pathways

• Reactome
• SIGNOR SIGNOR paper