Suggestions for RefGen jamboree annotation targets (Archived): Difference between revisions

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|(SGD:S000005429; SGD:S000005936; SGD:S000005551; SGD:S000002599; SGD:S000002200) ~640 [even if we chose to do JUST SIR2 and not the related 4 proteins, that would still be 592 papers]
|(SGD:S000005429; SGD:S000005936; SGD:S000005551; SGD:S000002599; SGD:S000002200) ~640 [even if we chose to do JUST SIR2 and not the related 4 proteins, that would still be 592 papers]
|(UniProtKB:O94640) ~1
|(UniProtKB:O94640) ~1
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| ELAC2 (tRNA 3'-processing endonuclease; defects are involved in prostate cancer)
|http://ppod.princeton.edu/cgi-bin/ppod.cgi/GO3/OrthoMCL1557
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|(SGD:S000001787) ~13
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|SURF1 (involved in assembly of cytochrome c oxidase; defects are a cause of Leigh syndrome)
|http://ppod.princeton.edu/cgi-bin/ppod.cgi/GO3/OrthoMCL1594
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|(SGD:S000003344) ~41
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|NIPBL (involved in sister chromatid cohesion; defects are the cause of Cornelia de Lange syndrome type 1 (CDLS1))
|http://ppod.princeton.edu/cgi-bin/ppod.cgi/GO3/OrthoMCL1223
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|(SGD:S000002588) ~ 45
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Revision as of 20:48, 16 December 2009

Please note here any genes that you think might be suitable for a Reference Genome jamboree.

All groups that participate in the jamboree should note the amount of literature that is available for each proposed target. Therefore the aim would be to select two targets for a jamboree that have the widest spread of literature across all participating groups.

In addition, please indicate your preferred date for the RefGen call, by visiting: http://www.doodle.com/a4h2u7hdcmqieiir

Target Gene Name PPOD URL Arabidopsis ID & papers Dicty ID & papers Drosophila ID & papers C.elegans ID & papers Chicken ID & papers E.coli ID & papers Human ID & papers Mouse ID & papers Rat ID & papers S.cerevisiae ID & papers S.pombe ID & papers Zebrafish ID & papers
WNT4 (Ligand for frizzled family of transmembrane receptors. Probable developmental protein. Possible signaling molecule which affects the development of discrete regions of tissues) http://ppod.princeton.edu/cgi-bin/ppod.cgi/GO3/OrthoMCL5001 none none none WB:WBGene00000857 (cwn-1 · K10B4.6) · UniProtKB:P34888

~17 papers

(UniProtKB:P56705)~70 (MGI:98957) ~65 (RGD:621348) ~40 (no ortholog) 0
SLIT2 (molecular guidance cue in cellular migration) http://ppod.princeton.edu/cgi-bin/ppod.cgi/GO3/OrthoMCL916 none none (UniProtKB:P24014, FB:FBgn0003425) ~100 WB:WBGene00004854 (F40E10.4 · slt-1) · UniProtKB:Q20204

~27 papers

(UniProtKB:O94813) ~60 (MGI:1315205) ~35 (RGD:69310) ~40 (no ortholog) 0
NFX1 (Nuclear transcription factor). In mammals may be involved in regulating duration of an inflammatory response) http://ppod.princeton.edu/cgi-bin/ppod.cgi/GO3/OrthoMCL3955 (TAIR:AT1G10170)(UniProtKB:Q9SY59) ~8 DDB_G0293590 : 1 HTP (UniProtKB:P40798, FB:FBgn0001978) ~3 WB:WBGene00007048 (C16A3.7 · tag-182) · UniProtKB:Q18034

0 papers

(UniProtKB:Q12986) ~8 (MGI:1921414) ~ 2 (RGD:1310277) - 0 (SGD:S000004968) 7
ATF6B (Cyclic AMP-dependent transcription factor ATF-6 beta) http://ppod.princeton.edu/cgi-bin/ppod.cgi/GO3/OrthoMCL4962 none none (UniProtKB:Q8SX87, FB:FBgn0033010) 0 WB:WBGene00000222 (F45E6.2 · atf-6) · UniProtKB:Q20435 (F45E6.2 · atf-6)

~9 papers

(UniProtKB:Q99941) ~40 (MGI:105121) ~ 3 (RGD:1303317) - 0 (no ortholog) 0
SIR2 (NAD-dependent histone deacetylase SIR2 of the Sirtuin family involved in regulation of lifespan, EC=3.5.1.-) http://ppod.princeton.edu/cgi-bin/ppod.cgi/GO3/Para1362 (TAIR:AT5G55760) (UniProtKB:Q9FE17) ~2 (UniProtKB:Q54GV7): DDB_G0289967 (sir2D): none (UniProtKB:Q9VK34, FB:FBgn0024291) ~11 WB:WBGene00004800 (R11A8.4 · sir-2.1) · UniProtKB:Q21921 (R11A8.4 · SIRT1_CAEEL · sir-2.1)

~40 papers

(UniProtKB:Q68BG0) (UniProtKB:P75960) (UniProtKB:Q96EB6) ~115 (MGI:2135607) ~ 49 (RGD:1308542) ~36 (SGD:S000005429; SGD:S000005936; SGD:S000005551; SGD:S000002599; SGD:S000002200) ~640 [even if we chose to do JUST SIR2 and not the related 4 proteins, that would still be 592 papers] (UniProtKB:O94640) ~1
ELAC2 (tRNA 3'-processing endonuclease; defects are involved in prostate cancer) http://ppod.princeton.edu/cgi-bin/ppod.cgi/GO3/OrthoMCL1557 (SGD:S000001787) ~13
SURF1 (involved in assembly of cytochrome c oxidase; defects are a cause of Leigh syndrome) http://ppod.princeton.edu/cgi-bin/ppod.cgi/GO3/OrthoMCL1594 (SGD:S000003344) ~41
NIPBL (involved in sister chromatid cohesion; defects are the cause of Cornelia de Lange syndrome type 1 (CDLS1)) http://ppod.princeton.edu/cgi-bin/ppod.cgi/GO3/OrthoMCL1223 (SGD:S000002588) ~ 45