XP:Progress 2008
Progress as of 2008/10/20
Motivation and Goals
- GO has become too large and complex to manage manually
- Errors of omission and commission negatively impact users in many ways
- Provide connections between GO and other ontologies
Methods
- Create computable logical definitions (Cross Products) for GO terms using (a) other GO terms (b) terms from other ontologies
- Use logic-based reasoning to find inconsistencies and errors
Results 2008
- We have XP defs for 10712/27589 of GO terms
- 1500-2000 links added or moved in GO based on reasoner results
| dynamic | spatial | |||||
|---|---|---|---|---|---|---|
| bioprocess | anatomic | chemical | ||||
| biological_process | molecular_function | cell | cellular_component | uberon | chebi | |
| biological_process | 4133 go_xp_regulationbiological_process_xp_self | 527 biological_process_xp_cell | 724 biological_process_xp_cellular_component | 516 biological_process_xp_uber_anatomy | 2901 go_xp_chebi | |
| molecular_function | molecular_function_xp_regulators | molecular_function_xp_regulators | go_xp_chebi | |||
| cellular_component | cellular_component_xp_go | cellular_component_xp_go | cellular_component_xp_self | |||
Internal Cross Products
Purely within GO