XP:Progress 2008

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Revision as of 17:43, 17 October 2008 by Cjm (talk | contribs) (→‎Results 2008)
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Progress as of 2008/10/20

Motivation and Goals

  • GO has become too large and complex to manage manually
  • Errors of omission and commission negatively impact users in many ways
  • Provide connections between GO and other ontologies

Methods

  • Create computable logical definitions (Cross Products) for GO terms using (a) other GO terms (b) terms from other ontologies
  • Use logic-based reasoning to find inconsistencies and errors

Results 2008

  • We have XP defs for 10712/27589 of GO terms
  • 1500-2000 links added or moved in GO based on reasoner results


caption
dynamic spatial
bioprocess anatomic chemical
biological_process molecular_function cell cellular_component uberon chebi
biological_process 4133 go_xp_regulation bp_xp_bp 527 bp_xp_cell 724 bp_xp_cc 516 bp_xp_uberon 2901 bp_xp_chebi
molecular_function 134 mf_xp_regulators 84 mf_xp_regulators 360 mf_xp_chebi
cellular_component 24 cc_xp_go 148 cc_xp_go 715 cc_xp_cc

Internal Cross Products

Purely within GO

Regulation Cross Products

Cellular Component internal xps

BP XP CC

External Cross Products

Uber Anatomy Ontology

CHEBI