XP:biological process xp sequence molecule: Difference between revisions

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The former is what is usually meant in terms with the string "telomere" or "telomeric"
The former is what is usually meant in terms with the string "telomere" or "telomeric"
=== Chromosome ===
Both SO and CC have chromosome
* SO:0000340 chromosome [DEF: "Structural unit composed of a nucleic acid molecule which controls its own replication through the interaction of specific proteins at one or more origins of replication."]
* GO:0005694 chromosome [DEF: "A structure composed of a very long molecule of DNA and associated proteins (e.g. histones) that carries hereditary information."]

Revision as of 20:27, 24 April 2008

CHEBI/SO overlaps

Bases and amino acids

  • inosine

etc

Peptide

  • peptide (SO has active_peptide as an EXACT synonym. mistake?)

SO/CC overlaps

Centromere

  • SO:0000577 centromere [DEF: "A region of chromosome where the spindle fibers attach during mitosis and meiosis."]
  • GO:0005698 centromere [DEF: "OBSOLETE. The region of a eukaryotic chromosome that is attached to the spindle during nuclear division. It is defined genetically as the region of the chromosome that always segregates at the first division of meiosis; the region of the chromosome in which no crossing over occurs. At the start of M phase, each chromosome consists of two sister chromatids with a constriction at a point which forms the centromere. During late prophase two kinetochores assemble on each centromere, one kinetochore on each sister chromatid."]
  • GO:0000775 chromosome, pericentric region [DEF: "The central region of a chromosome that includes the centromere and associated proteins. In monocentric chromosomes, this region corresponds to a single area of the chromosome, whereas in holocentric chromosomes, it is evenly distributed along the chromosome."] comment: This term was made obsolete because it is genetically defined region and not a specific subcellular localization.

GO has the following:

GO:0030702 chromatin silencing at centromere 
GO:0031055 chromatin remodeling at centromere 
GO:0031059 histone deacetylation at centromere 
GO:0031066 regulation of histone deacetylation at centromere 
GO:0031067 negative regulation of histone deacetylation at centromere 
GO:0031068 positive regulation of histone deacetylation at centromere 
GO:0034080 DNA replication-independent nucleosome assembly at centromere 
GO:0043505 centromere-specific nucleosome 
GO:0051756 meiotic sister chromatid centromere separation

Telomere

Similar comments apply

Here there are two GO terms to choose from:

  • GO:0000781 chromosome, telomeric region (related synonym: telomere)
  • GO:0000782 telomere cap complex

The former is what is usually meant in terms with the string "telomere" or "telomeric"

Chromosome

Both SO and CC have chromosome

  • SO:0000340 chromosome [DEF: "Structural unit composed of a nucleic acid molecule which controls its own replication through the interaction of specific proteins at one or more origins of replication."]
  • GO:0005694 chromosome [DEF: "A structure composed of a very long molecule of DNA and associated proteins (e.g. histones) that carries hereditary information."]