5 March 2019 PAINT Conference Call
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Family Curation status
Huaiyu -> SQL query: 6,500 families done
- There are still 4 open tickets in the PAINT pipeline project:
https://github.com/orgs/geneontology/projects/23 Status update on these?
- Duplicate annotation problem is back:
New families and fixing GitHub tickets (40 open as of Feb 27)
Tool feature requests
- Links to AmiGO for all genes
Specificity of transporters
First issue: Questionable dispute
- Val points out that transporter substrate may evolve rapidly; we need to be careful when we annotate.
- In this case the annotation was propagated to only a small node; what do people think about this propagation?
Second issue: questionable tree annotation
- Review annotations to this family: PTHR43341
- why did the curator NOT propagate 'amino acid transporter activity' ?
- Weird propagation in a small pombe duplication node
- No membrane annotation
- Hardly any BP propagated
- Could this be due to some automatic update ?