Acts upstream of, positive effect
A gene product 'acts upstream of, positive effect' of a biological process if its activity (MF) is: 1) executed before the beginning of the process, 2) is not part of the process, and 3) is required for the process to occur.
- c 'acts upstream of, positive effect' p if c is enables f, and f is causally upstream of p, and the direction of f is positive
Examples of Usage
Genes involved in Ras lipidation act usptream of, postive effect in Ras protein signal transduction
- Ras signal transduction
- Regulation of Ras localization and cell transformation by evolutionarily conserved palmitoyltransferases.
Genes involved in glycine transport into the mitochondrion act upstream of, positive effect in heme biosynthesis
Quality Control Checks
Last reviewed: March 9, 2018