Annotation Extension Relation:acts on population of

From GO Wiki
Jump to navigation Jump to search

Back to Annotation usage examples for each annotation extension relation

Relations Ontology

Definition

  • Current RO definition: p acts on population of c iff c' is a collection, has members of type c, and p has participant c
  • Previous GO_REL definition: The relationship that links an entity with a process in which the process has more than one participant that is of the same entity type.

Child terms

  • None.

Scope of use

Domain

GO:0003674 (molecular_function) or GO:0008150 (biological_process)

Range

CL:0000000 (cell) or GO:0005575 (cellular component) or WBbt:0004017 (cell)

Annotation Extension Usage Examples

1. Hematopoietic dysfunction in a mouse model for Fanconi anemia group D1:

Statement from paper:

Data obtained at 30 days posttransplantation showed that the CRA of Brca2Δ27/Δ27 BM cells was markedly below that corresponding to WT BM cells (Fig. 5B). Furthermore, CRA values from Brca2Δ27/Δ27 BM progressively dropped as the posttransplantation time was increased (Fig. 5B), indicating that, at least under the proliferative stress mediated by a BM transplantation, the repopulating function of Brca2Δ27/Δ27 HSCs is markedly impaired.


Gene Name (col 2) GO ID (col 5) Reference (col 6) Evidence (col 7) Annotation Extension (col 16)
MGI:MGI:109337 Brca2 GO:0008283 cell population proliferation PMID:GO:0008283 IMP acts_on_population of(CL:0000037 hematopoietic stem cell)

Using example (from above) to demonstrate Folding_and_Unfolding using the relationship acts_on_population_of

1. SEMA3A signals through NRP1 and PLXNA4 to guide the axons of facial visceromotor neurons:

Folded/unfolded Gene Name (col 2) GO ID (col 5) Reference (col 6) Evidence (col 7) Annotation Extension (col 16) Parent terms of new folded GO term
Unfolded MGI:MGI:109337 Brca2 GO:0008283 cell population proliferation PMID:16859999 IMP acts_on_population of(CL:0000037 hematopoetic stem cell)
Folded MGI:MGI:109337 Brca2 New GO ID hematopoetic stem cell population proliferation PMID:16859999 IMP is_a GO:0008045 cell population proliferation



Date last reviewed: 2020-12-11

Back to Annotation usage examples for each annotation extension relation