Currency chemicals

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This is a list of chemicals that are generally considered 'inputs' and 'outputs' for chemical reactions (GO molecular functions), in contrast to 'primary inputs' and 'primary outputs', that represent the biologically relevant substrate and products of the activity, respectively.

Note that many of these chemicals are synthesized by the cell (ATP, FAD, CoA, etc); and therefore there are reactions for which these chemicals are considered 'primary inputs' and 'primary outputs'.

GO Currency chemicals
Chemical Official ChEBI label ChEBI ID
H2O water CHEBI:15377
AMP adenosine 5'-monophosphate(2−) CHEBI:456215
ADP ADP(3−) CHEBI:456216
ATP ATP(4−)  CHEBI:30616
dAMP 2'-deoxyadenosine 5'-monophosphate(2−) CHEBI:58245
dADP dADP(3−) CHEBI:57667
dATP dATP(4−) CHEBI:61404
GMP guanosine 5'-monophosphate(2−) CHEBI:58115
GDP GDP(3−) CHEBI:58189
GTP GTP(4−) CHEBI:37565
dGMP 2'-deoxyguanosine 5'-monophosphate(2−) CHEBI:57673
dGDP dGDP(3−) CHEBI:58595
dGTP GTP(4−) CHEBI:37565
UMP uridine 5'-monophosphate(2−) CHEBI:57865
UDP UDP(3−) CHEBI:58223
UTP UTP(4−) CHEBI:46398
dUTP dUTP(4−) CHEBI:61555
H+ hydron CHEBI:15378
O2 dioxygen CHEBI:15379
CO2 carbon dioxide CHEBI:16526
Pi hydrogenphosphate CHEBI:43474
PPi diphosphate(3−) CHEBI:33019
NAD+ NAD(1−) CHEBI:57540
NADH NADH(2−) CHEBI:57945
NADP+ NADP(3−) CHEBI:58349
NADPH NADPH(4−) CHEBI:57783
FAD FAD(3−) CHEBI:57692
FADH2 FADH2(2−) CHEBI:58307
CoA coenzyme A(4−) CHEBI:57287


Source of the data

This list was obtained from Reactome, see https://github.com/geneontology/go-ontology/issues/26900.

Review Status

Last reviewed: 2024-02-06

Reviewed by: Pascale Gaudet