Enzyme binding

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PROBLEM

GO:0019903 protein phosphatase binding
GO:0051721 protein phosphatase 2A binding
GO:0008157 protein phosphatase 1 binding
GO:0030346 protein phosphatase 2B binding
  • Q: Can these terms be used to annotate proteins that bind to regulatory subunits of the phosphatase, or just the catalytic subunit.
  • Q: Many proteins bind to a regulatory subunit and stop the subunit from binding to the catalytic subunit, so you can't change them to binding to a complex.
  • NB: In some cases both subunits are required to form a functional phosphatase.
  • NB: The same issue will apply to kinase binding terms.


RELATED SOURCEFORGE ITEM

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