Noctua to Standard Annotation Conversion Table

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Noctua to Standard Annotation Conversion Table (work in progress)

In Google doc for now: https://docs.google.com/spreadsheets/d/1vkBVTyUg1tjipUtYGan5Ob0vE14H_j6O-PuTH9619eg/edit#gid=0


Molecular Function
 Link  Curation Statement Allowed values (range)  GO-CAM GPAD Output
GO-CAM relation GO-CAM statement GPAD relation (gene product-to-term) GPAD example (gene product-to-term) GPAD annotation extension relation (see note below) GPAD example (annotation extension)
MF to Annotated Entity The molecular activity described by the GO MF is enabled by the annotated entity. genes, gene products, protein-containing complexes enabled by protein kinase activity enabled by PLK1 enables PLK1 enables protein kinase activity n/a n/a
MF to Location The molecular activity described by the GO MF occurs_in a physical location. GO cellular component, cells, higher anatomical structures (e.g. tissues), organisms occurs_in protein kinase activity enabled by PLK1 occurs_in cytosol part of PLK1 part of cytosol occurs_in PLK1 enables protein kinase activity

AE: occurs_in cytosol

MF to Input The molecular activity described by the GO MF has input one or more entities whose state is changed (bound, transported, modified, consumed, or destroyed) by the activity. genes, gene products, protein-containing complexes, chemicals has input protein kinase activity enabled by PLK1 has input KAT7 enables PLK1 enables protein kinase activity has input has input KAT7
MF to Output The molecular activity described by the GO MF has output one or more entities whose state was changed (bound, transported, modified, consumed, or destroyed) by the activity. genes, gene products, protein-containing complexes, chemicals has output protein kinase activity enabled by PLK1 has output phosphorylated KAT7 enables PLK1 enables protein kinase activity has output has output phosphorylated KAT7
MF to Temporal Phase The molecular activity described by the GO MF happens during a specific temporal or developmental stage. biological phases (e.g. cell cycle phases), developmental stages (e.g. larval stage) happens during protein kinase activity enabled by PLK1 happens during S phase enables PLK1 enables protein kinase activity happens during happens during S phase
MF providing an input for another MF The molecular activity described by an upstream GO MF that directly provides input for for a downstream MF. The two activities act consecutively. The intended use is to connect catalytic activities that are part of a metabolic pathway. GO molecular function directly provides input for 6-phosphofructokinase activity enabled by PFK

directly provides input for fructose bisphosphate aldolase activity enabled by ALDOA

enables PFK enables 6-phosphofructose kinase activity directly provides input for directly provides input for fructose bisphosphate aldolase activity
MF part of a BP The molecular activity enabled by a gene product is an integral part of the BP. GO molecular function part of 6-phosphofructokinase activity enabled by PFK part of glycolytic process through fructose-6-phosphate involved in PFK involved in glycolytic process through fructose-6-phosphate
  • Annotation Extensions are only output in the GPAD file if the evidence (evidence code, reference, and with/from, if applicable) for the primary annotation and the annotation extension is the same.

Review Status

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