2014 Barcelona GOC Meeting Agenda
COMING SOON .....
Day1-Curation and Annotations
Curation paradigms and documentations
- With/From field cardinality proposal(Rachael 30-45min) (Decisions: what is the cardinality of the with field for each evidence code? Can we use pipes/commas consistently as we do for extensions? If an 'AND is converted to an 'OR' is this really a weaker statement or a different statement-do we need a 3rd delimiter?)
- Annotation extension relationships: how to use them (Ruth)
- Discussion of catabolism and biosynthesis (Pascale)
- Discussion on 'protein dimerization activity' vs. e.g. 'protein homotetramerization' (MF vs BP). See summary here: http://sourceforge.net/p/geneontology/ontology-requests/11087/ (Paola)
and https://sourceforge.net/p/geneontology/ontology-requests/10909/
- Refresher/overview of available TG templates (Jane)
- Use of expanded evidence codes and interactions with ECO (Kimberley, with input from others - 15-20 minutes)
- Are any groups currently using expanded ECO codes for GO annotation?
- Can existing tools (Protein2GO, GO web site, AmiGO) accommodate the codes?
- Any reasons not to start using expanded ECO codes? Is turn around time for new ECO term requests sufficent?
Not directly GO related
- Monique Zahn: Quality control process in neXtProt (about 15 minutes)
Common Curation Environment
- Common Annotation Environment
The objective is to have environment into which all curators can enter data and from which each group can extract data files.
- LEGO models of annotation extensions (David OS)
- Noctua development (Suzi?)
- CAT (is this still under development or subsumed under Noctua?)(Kimberley?)
- Update on Protein2GO, including annotation to IntACT IDs (Tony 15-20mins)
PAINT
- PAINT Jamboree debrief, future directions (Huaiyu, Pascale)
- Autophagy in PAINT: lessons learned (Marc F, Pascale)
Day2-Ontology Development and Priorities
- Clarity vs Expressiveness in GO - striking a balance (David OS working on a white paper on this).
- Progress in moving GO editing and annotation extension relations to OWL. (David OS)
- Pilot project to replace NCI thesaurus 'biological process' branch with GO biological process (Chris)
- GO and human disease (Chris)
- High-level protein family classification (Jane)
- Proposed changes to Molecular Function (Jane)
Day3-UserSupport including AmiGO and Enrichment Analysis
- GO site/docs development (Moni, Seth)
- AmiGO feedback and development (Seth)
- GO Help Desk
- Adding people to the rota
- Assigning the help desk
- adding to FAQ
- GO Enrichment Analysis (Judy, Paul, others)
- report on needs/ improvements in AmiGO tool (Seth, Paul, Rama)
- intersection with Panther db often down
- Judy working on white paper 'Gene Enrichment Anaysis using the GO: the good, the bad, the ugly.' I will have early draft at meeting.
- report on needs/ improvements in AmiGO tool (Seth, Paul, Rama)