2nd Nov 2022 PAINT Conference call
Present
Marc, Pascale, Huaiyu, Dustin, Anushya, Paul
Agenda
PANTHER17.0 release update
PANTHER 17 is released and now supported in PAINT after QC and validation were performed.
Release stats folder: https://drive.google.com/drive/folders/1OokW5IfD2zx4wLGlacwqy0uj3G3DIUtP
Summary stats:
- IBA annotation change: -7.91% (-316642 IBAs) Google sheet
- Compares last 15.0 IBA release (from 2022-09-26) against the new 17.0 IBA release.
- New IBA GAF release uses new code to remove redundant term annotations. This reduced IBA count by 2.95%.
- Families where IBD, IKR, IRD counts changed: 1447 Google sheet
- Families that "require paint review": 1674 Google sheet
- Families that lost all PAINT annotations: 175 Google sheet
New PAINT software release on Oct.31st, 2022
The build has the following updates:
- Landing page (http://paintcuration.usc.edu/) now displays version of UPL and Full GO version release date.
- Updated to refer to UPL17 data
- Updated to handle Domain information from family library file system. This will improve performance
- Added handling for active site information. This can be accessed in the MSA tab via Menu MSA and Domain->Key Residue. Any sequence with active site information will be displayed in bold face. Mouse over the amino acid to view active site information. Coloring is as follows:
- Active site – black
- Binding – Red
- Metal – Orange
- Multiple residue types – Magenta
- Updated for code cleanup and optimization
Continue discussing PAINT human paper
Here is the link to the manuscript:
https://docs.google.com/document/d/1-8wVCPg7GEZQ9l3ox85hBO48YBoknRXOG_B9AJ6YZ0Q/edit?usp=sharing