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Group Leaders

David Hill (MGI) and Kimberly Van Auken (WB)

Mission statement

  • Educate GOC curators about best annotation practice
  • Enforce annotation rules/policies within GOC
  • Maintain the annotation/evidence code documentation
  • Train/assist new groups with annotations
  • Educate and keep all the annotating groups up-to-date with changes in file formats
  • Keep contributing groups up-to-date with ontology development and how it affects annotations

Annotation Documentation

Annotation Documentation Table of Contents

Overview of GO annotations

Introduction to GO annotations on the GO website

Elements of an annotation

Tips to Produce High Quality Annotations

General guidance to submit annotations to the GO consortium

Annotation maintenance

Annotation Quality Control

Ontology-Specific Guidelines

Molecular Function

Cellular Component

Biological Process

Annotation Relations

Annotation Extensions

Topic-Specific Guidelines

Annotating from phenotypes

Topic-Specific Guidelines under review

Annotating regulation

Annotating binding

Annotating downstream processes

Annotating ligand-receptor pathways

Response to x annotation guidelines

Multi-species processes


Apoptosis Curation Manual

Transcription Annotation Guide (updated May 2020)


Guidelines for checkpoints

Guide to GO Evidence Codes

Experiment-Specific Annotation Guidelines - in progress

Noctua and GO-CAM

Noctua Curation Guide

Importing MOD annotations into Noctua


Annotation Conference Calls


  • Calls are held on Tuesdays at 4:00pm GMT, 11:00am EST, 8:00am PST
  • Calls are scheduled on the GO's Google calendar. Please request access to the calendar if you don't have it.
  • Reminder emails are sent out to the go-consortium mailing list; sign up here.

How to Join

  • Please consult the GO calendar for the meeting URL.
  • to join via phone: enter Meeting ID found on the GO calendar after dialing in
  • from US: +1 408 638 0968 (US Toll) or +1 646 558 8656 (US Toll)
  • from UK: +44 (0) 20 3695 0088 or +44 (0) 80 0031 5717
  • from Switzerland: +41 (0) 31 528 0988 or +41 800 002 622

Agenda and Minutes

  • Please contact David and Kimberly if there are items you would like to add to the agenda

GO-CAM and Noctua Calls

Note that as of 2020, we are no longer distinguishing GO-Annotation and GO-CAM/Noctua calls.

We will meet regularly on Tuesdays at 8am PST to discuss annotation issues related to both standard and GO-CAM annotation.

Agenda and Minutes

GO Annotation on GitHub

  • The Gene Ontology uses an issue tracker hosted on GitHub to record and track annotation issues.
  • The go-annotation repo on GitHub may be accessed here.
  • Contact information for each group that contributes to the consortium is available here

GO Annotation on gitter

  • The GO annotation group uses gitter as an informal chat service.
  • Curators are free to ask questions or share ideas on gitter, with issues elevated to more formal tracking (i.e. github/go-annotation or wiki documentation), as needed.
  • Curators can login to gitter using their github accounts.

GO Annotation on Google Drive

  • The Gene Ontology uses Google drive to host notes and spreadsheets for annotation review and annotation working groups.
  • The GO Annotation folder on Google Drive may be accessed here.

GO Consortium Mailing List

  • Reminders about conference calls are sent to the go-consortium mailing list.
  • To subscribe to the go-consortium mailing list, please click here.

Focused annotation projects


Intro to GO

To delete, archive, or retire

To review


Archived Pages