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Group Leaders

Pascale Gaudet and Kimberly Van Auken

Mission statement

  • Educate GOC curators about best annotation practice
  • Enforce annotation rules/policies within GOC
  • Maintain the annotation/evidence code documentation
  • Train/assist new groups with annotations
  • Educate and keep all the annotating groups up-to-date with changes in file formats
  • Keep contributing groups up-to-date with ontology development and how it affects annotations

Annotation Documentation

Annotation Guidelines

General Annotation Documentation

Topic Status Last reviewed
General introduction to GO annotation - GO website Current 2021-01-27
Elements of an annotation Current 2019-04-11
Guide to GO Evidence Codes Current 2018-02-23
Tips to Produce High Quality Annotations Current 2019-04-11
Annotation Relations Draft
Annotation Extensions
Annotation Extensions - Summary  Current 2021-06-10
Annotation Extensions To be reviewed
Annotation Extension: Capturing cell and tissue types To be reviewed
Annotation Extension: Capturing participants To be reviewed

Topic-Specific Guidelines

Topic Status Last reviewed
Annotating from phenotypes Current 2018-12-18
Apoptosis Curation Manual
MicroRNA_GO_annotation_manual Current 2020-03-23
Transcription factors annotation manual Current 2021-06-09
 Chromatin remodeling  In progress  2022-08-23
Non-catalytic Molecular Functions Current 2022-05-19
Annotating binding Draft 2020-05-04
Annotating ligand-receptor pathways To be reviewed > 5 years old
Annotating regulation To be reviewed > 5 years old
Annotating downstream processes Draft
Guidelines for checkpoints To be reviewed
Response to x annotation guidelines To be reviewed
Multi-species processes To be reviewed
Experiment-Specific Annotation Guidelines Draft

Noctua and GO-CAM

Topic Status Last reviewed
Noctua Curation Guide Current 2021-
ART Documentation Current 2021-05-26
Importing MOD annotations into Noctua Draft 2021-

Annotation quality control

Topic Status Last reviewed
Annotation Review Request Current 2022-04-22
Annotation maintenance Current 2020-08-20
Proposal for Author Feedback for annotations  Draft  2019-04-16
QC procedures from contributing groups Draft 2019-03-14

Guidelines for new Groups/new submissions

Topic Status Last reviewed
General guidance to submit annotations to the GO consortium Under review > 5 years ago


Annotation Conference Calls


  • Calls are held on Tuesdays at 4:00pm GMT, 11:00am EST, 8:00am PST
  • Calls are scheduled on the GO's Google calendar. Please request access to the calendar if you don't have it.
  • Reminder emails are sent out to the go-consortium mailing list; sign up here.

How to Join

  • Please consult the GO calendar for the meeting URL.
  • to join via phone: enter Meeting ID found on the GO calendar after dialing in
  • from US: +1 408 638 0968 (US Toll) or +1 646 558 8656 (US Toll)
  • from UK: +44 (0) 20 3695 0088 or +44 (0) 80 0031 5717
  • from Switzerland: +41 (0) 31 528 0988 or +41 800 002 622

Agenda and Minutes

  • Please contact Kimberly if there are items you would like to add to the agenda

GO-CAM and Noctua Calls

Note that as of 2020, we are no longer distinguishing GO-Annotation and GO-CAM/Noctua calls.

We will meet regularly on Tuesdays at 8am PST to discuss annotation issues related to both standard and GO-CAM annotation.

Agenda and Minutes

GO Annotation on GitHub

  • The Gene Ontology uses an issue tracker hosted on GitHub to record and track annotation issues.
  • The go-annotation repo on GitHub may be accessed here.
  • Contact information for each group that contributes to the consortium is available here

GO Annotation on Slack

  • The GO consortium uses GO Slack as an informal chat service.
  • Curators are free to ask questions or share ideas on Slack, with issues elevated to more formal tracking (i.e. github/go-annotation or wiki documentation), as appropriate.

GO Annotation on Google Drive

  • The Gene Ontology uses Google drive to host notes and spreadsheets for annotation review and annotation working groups.
  • The GO Annotation folder on Google Drive may be accessed here.

GO Consortium Mailing List

  • Reminders about conference calls are sent to the go-consortium mailing list.
  • To subscribe to the go-consortium mailing list, please click here.

Focused annotation projects


Intro to GO

To delete, archive, or retire

To review


Archived Pages