Annotation Conf. Call, February 25, 2014

Agenda

• David OS will talk about formalizing the representation of symbiotic relationships and annotations to describe them in the ontology
  • GO annotations include many that involve an interaction between two organisms.

These include: annotation to a cell component of the host of the organisms expressing the gene being annotated. annotation to a biological process involving a virus and and its host. In these cases we have a mechanism for recording multiple taxon IDs for interacting organisms, but not the relationship between the two organisms , e.g one might be host to the other or vector for the other. We also don't have a way to record which of the two interacting organisms a cell component is located in or a biological process is occurring in. My proposal aims to solve this problem, by allowing annotators to link taxon IDs using a relationship such as host_of or vector_for. Additionally you will be able to use annotation extension to record which of the two organisms an annotated CC is located in or a biological process occurs in. Along with this extension to annotation, I plan to rearrange parts of the CC hierarchy - particularly those relating to host cell. My presentation will include details of these changes.

• Requesting new GO Complex terms (Jane)

• E2/E3 terms (David Hill)