Annotation Conf. Call 2019-05-14

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GOC meeting debrief/announcements


  • Remind people about Gitter as an option to communicate with other curators

Transcription Factor Annotations

  • TF annotations: All: People will need to migrate transcription factor annotations to specific TF binding terms to use GO+SO extensions

Only 2 terms found in SO so far:

 EXP annotations GO term SO term
114 GO:0070888 E-box binding SO:0001158 E_box_motif
12 GO:0035497 cAMP response element binding SO:0001843 CRE
10 GO:0034056 estrogen response element binding
3 GO:0035538 carbohydrate response element binding
2 GO:0070594 juvenile hormone response element binding
3 GO:0071820 N-box binding
8 GO:0044323 retinoic acid-responsive element binding
5 GO:0010736 serum response element binding
4 GO:0032810 sterol response element binding
5 GO:0070644 vitamin D response element binding


  • Remind people they can provide guidance for PAINT annotation: PAINT Annotations: to prevent over-propagation to paralogs: submit GitHub tickets explaining that the list of gene products associated with this process is complete and that paralogs should not be associated with the term.

Annotation Pipelines

  • Annotation pipelines and guidelines: We'd like to have information about each group's annotation guidelines and how annotations are processes and presented/exporter to users.
  • This is somewhat more detailed information on annotation file management than what we were able to collect on the survey.
  • Laying the groundwork for more consistency in annotation.
    • What do groups import? What do groups filter?
  • WB and Zfin have added their documentation.

MOD Import into Noctua

Matrisome Project

  • Several in-silico analyses for different organisms have produced a protein set identified as the 'matrisome' - comprehensive list of ECM proteins
  • Rachael Huntley annotated mammalian matrisome
  • Other groups have been contacted - WB, FlyBase, Zfin (?)
  • It would be good to make sure we are annotating this work consistently
  • Future call to discuss?


  • Present: David, Dmitry, Dustin, Edith, Giulia, Harold, Helen, Judy, Karen, Kevin M, Laurent-Philippe, Li, Marie-Claire, Midori, Pascale, Patrick M, Petra, Rob, Sabrina, Shur-Jen, Stacia, Suzi A, Tanya