Annotation Conf. Call July 9, 2013

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Agenda

QC check for Enzyme binding

  • We would like to propose that there shouldn't be any direct annotations to 'enzyme binding' term. We will add a 'not for direct annotation' tag to this term.

Protein oligomerization

Continuing our discussion on Protein oligomerization, we want to bring up some options to curtors.

  • Protein di/tri/oligomerization terms: In many cases where the functional unit is a hetero or homo dimer or oligmer, the best option would be to use col-16 to indicate the functional unit using a PRO ID.
  • In cases where geneproduct A is involved in the oligomerization of another gene product B, then the appropriate term would protein complex assembly and indicate the complex in col-16.

Protein binding annotations

  • Moving protein binding to its own file. Chris came up with the idea of keeping the protein binding terms in the GO, but moving protein binding annotations to its own file (separate from the main GAF for each group). This seems like a good solution that will make both parties happy.
    • if we did that and if protein binding was the sole annotation for the gp, should we say function unknown in the main GAF?
    • or we could have unknown and protein binding annotation together to indicate that the function is unknown but it interacts with something.