Annotation Conf. Call June 11, 2013: Difference between revisions
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[[Category:Annotation Working Group]] | |||
==Agenda== | ==Agenda== | ||
===Confusing terms=== | |||
** protein dimerization, oligomerization etc. | ** protein dimerization, oligomerization etc. | ||
Process terms: | Process terms: | ||
GO:0006461 protein complex assembly | GO:0006461 protein complex assembly | ||
GO:0035786 protein complex oligomerization | GO:0035786 protein complex oligomerization | ||
GO:0051259 protein oligomerization | GO:0051259 protein oligomerization | ||
GO:0051260 protein homooligomerization | GO:0051260 protein homooligomerization | ||
GO:0051291 protein heterooligomerization | GO:0051291 protein heterooligomerization | ||
GO:0051262 protein tetramerization | GO:0051262 protein tetramerization | ||
GO:0051289 protein homotetramerization | GO:0051289 protein homotetramerization | ||
GO:0051290 protein heterotetramerization | GO:0051290 protein heterotetramerization | ||
GO:0070206 protein trimerization | GO:0070206 protein trimerization | ||
GO:0070207 protein homotrimerization | GO:0070207 protein homotrimerization | ||
GO:0070208 protein heterotrimerization | GO:0070208 protein heterotrimerization | ||
GO:0034214 protein hexamerization | GO:0034214 protein hexamerization | ||
...and regulation terms | ...and regulation terms | ||
Function terms: | Function terms: | ||
GO:0046983 protein dimerization activity | GO:0046983 protein dimerization activity | ||
GO:0042803 protein homodimerization activity | GO:0042803 protein homodimerization activity | ||
GO:0046982 protein heterodimerization activity | GO:0046982 protein heterodimerization activity | ||
1. Should we represent these in the ontology? | 1. A protein binding to itself is not its function. Oligomeric state of a protein is indicative of its physical properties, not something we want to capture in GO. | ||
Should we represent these in the ontology? | |||
2. If so, we need guidelines for their use | 2. If so, we need guidelines for their use | ||
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and http://wiki.geneontology.org/index.php/2010_GO_camp_Annotation_of_complexes_issues | and http://wiki.geneontology.org/index.php/2010_GO_camp_Annotation_of_complexes_issues | ||
===Next GO meeting=== | |||
4-6th October 2013, Bar Harbor. Please register, details here: http://wiki.geneontology.org/index.php/2013_Bar_Harbor_Logistics | |||
Latest revision as of 16:45, 9 April 2014
Agenda
Confusing terms
- protein dimerization, oligomerization etc.
Process terms:
GO:0006461 protein complex assembly
GO:0035786 protein complex oligomerization
GO:0051259 protein oligomerization
GO:0051260 protein homooligomerization
GO:0051291 protein heterooligomerization
GO:0051262 protein tetramerization
GO:0051289 protein homotetramerization
GO:0051290 protein heterotetramerization
GO:0070206 protein trimerization
GO:0070207 protein homotrimerization
GO:0070208 protein heterotrimerization
GO:0034214 protein hexamerization
...and regulation terms
Function terms:
GO:0046983 protein dimerization activity
GO:0042803 protein homodimerization activity
GO:0046982 protein heterodimerization activity
1. A protein binding to itself is not its function. Oligomeric state of a protein is indicative of its physical properties, not something we want to capture in GO.
Should we represent these in the ontology?
2. If so, we need guidelines for their use
Previous discussions are here: http://wiki.geneontology.org/index.php/Jamboree_18_July_2008-minutes and http://wiki.geneontology.org/index.php/2010_GO_camp_Annotation_of_complexes_issues
Next GO meeting
4-6th October 2013, Bar Harbor. Please register, details here: http://wiki.geneontology.org/index.php/2013_Bar_Harbor_Logistics