Has small molecular activator: Difference between revisions
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| Line 63: | Line 63: | ||
!Reference (Col 6) | !Reference (Col 6) | ||
!Extension (Col 16) | !Extension (Col 16) | ||
!Parent terms for new folded GO term | |||
|- | |- | ||
| Unfolded | | Unfolded | ||
| Line 70: | Line 71: | ||
|PMID:12381728 | |PMID:12381728 | ||
|activated_by (ChEBI:29105, <span style="color:green">zinc ions</span>) | |activated_by (ChEBI:29105, <span style="color:green">zinc ions</span>) | ||
| | |||
|- | |- | ||
| Folded | | Folded | ||
| Line 76: | Line 78: | ||
|New GO term <span style="color:green">zinc activated ligand-gated ion channel activity</span> | |New GO term <span style="color:green">zinc activated ligand-gated ion channel activity</span> | ||
|PMID:12381728 | |PMID:12381728 | ||
| | | | ||
|is_a GO:0048471 <span style="color:red">ligand-gated ion channel activity</span> | |||
|- | |- | ||
|} | |} | ||
Revision as of 10:54, 9 May 2014
Definition
Identifies a chemical substance that increases the activity of the gene product.
Comment
This relation should not be used to annotate one gene product regulating another's activity; a regulator Molecular Function or regulation Biological Process should be used in such cases.
Synonyms
activated_by_chemical (EXACT)
activated_by_substance (EXACT)
activity_increased_by (EXACT)
Child terms
- None.
Scope of use
Domain
GO:0003674 ! molecular_function
Range
CHEBI:24431 ! chemical entity
Annotation Extension Usage Examples
Specifying that a gene product is activated by a specific chemical
1. zinc activated ligand-gated ion channel (ZACN) is activated by Zn2+, PMID:12381728
So the annotation would be:
| DB (Col 2) | Object (Col 3) | GO ID (Col 5) | Reference (Col 6) | Extension (Col 16) |
|---|---|---|---|---|
| Q401N2 | ZACN | GO:0048471 | PMID:12381728 | activated_by (ChEBI:29105, zinc ions) |
Using examples to demonstrate Folding_and_Unfolding using the relationship activated_by
1. zinc activated ligand-gated ion channel (ZACN) is activated by Zn2+, PMID:12381728
| Folded/unfolded | DB (Col 2) | Object (Col 3) | GO ID (Col 5) | Reference (Col 6) | Extension (Col 16) | Parent terms for new folded GO term |
|---|---|---|---|---|---|---|
| Unfolded | Q401N2 | ZACN | GO:0048471 ligand-gated ion channel activity | PMID:12381728 | activated_by (ChEBI:29105, zinc ions) | |
| Folded | Q401N2 | ZACN | New GO term zinc activated ligand-gated ion channel activity | PMID:12381728 | is_a GO:0048471 ligand-gated ion channel activity |
Back to Annotation usage examples for each annotation extension relation