Acts on population of
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Relations Ontology
Definition
- Current RO definition: p acts on population of c iff c' is a collection, has members of type c, and p has participant c
- Previous GO_REL definition: The relationship that links an entity with a process in which the process has more than one participant that is of the same entity type.
Child terms
- None.
Scope of use
Domain
GO:0003674 (molecular_function) or GO:0008150 (biological_process)
Range
CL:0000000 (cell) or GO:0005575 (cellular component) or WBbt:0004017 (cell)
Annotation Extension Usage Examples
1. Hematopoietic dysfunction in a mouse model for Fanconi anemia group D1:
Statement from paper:
Data obtained at 30 days posttransplantation showed that the CRA of Brca2Δ27/Δ27 BM cells was markedly below that corresponding to WT BM cells (Fig. 5B). Furthermore, CRA values from Brca2Δ27/Δ27 BM progressively dropped as the posttransplantation time was increased (Fig. 5B), indicating that, at least under the proliferative stress mediated by a BM transplantation, the repopulating function of Brca2Δ27/Δ27 HSCs is markedly impaired.
| Gene Name (col 2) | GO ID (col 5) | Reference (col 6) | Evidence (col 7) | Annotation Extension (col 16) |
|---|---|---|---|---|
| MGI:MGI:109337 Brca2 | GO:0008283 cell population proliferation | PMID:GO:0008283 | IMP | acts_on_population of(CL:0000037 hematopoietic stem cell) |
Using example (from above) to demonstrate Folding_and_Unfolding using the relationship acts_on_population_of
1. SEMA3A signals through NRP1 and PLXNA4 to guide the axons of facial visceromotor neurons:
| Folded/unfolded | Gene Name (col 2) | GO ID (col 5) | Reference (col 6) | Evidence (col 7) | Annotation Extension (col 16) | Parent terms of new folded GO term |
|---|---|---|---|---|---|---|
| Unfolded | MGI:MGI:109337 Brca2 | GO:0008283 cell population proliferation | PMID:16859999 | IMP | acts_on_population of(CL:0000037 hematopoetic stem cell) | |
| Folded | MGI:MGI:109337 Brca2 | New GO ID hematopoetic stem cell population proliferation | PMID:16859999 | IMP | is_a GO:0008045 cell population proliferation |
Date last reviewed: 2020-12-11
Back to Annotation usage examples for each annotation extension relation