Annotation Extension Relation:has regulation target: Difference between revisions
Line 64: | Line 64: | ||
|- | |- | ||
| Unfolded | | Unfolded | ||
| | | WBGene00000220 <span style="color:green">atf-2(tm467)</span> | ||
| GO: | | GO:0000122 <span style="color:green">negative regulation of transcription from RNA polymerase II promoter</span> | ||
| PMID: | | PMID:21502138 | ||
| | | IMP | ||
| has_regulation_target( | | has_regulation_target(WB:WBGene00000247 <span style="color:green">bec-1</span>)|has_regulation_target(WB:WBGene00002980 <span style="color:green">lgg-1</span> | ||
|- | |- | ||
| Folded | | Folded | ||
| | | WBGene00000220 <span style="color:green">atf-2(tm467)</span> | ||
| GO: | | GO:0000122 <span style="color:green">negative regulation of transcription from RNA polymerase II promoter</span> | ||
| PMID: | | PMID:21502138 | ||
| | | IMP | ||
| | | | ||
| <span style="color:red">No new GO term created</span> | | <span style="color:red">No new GO term created</span> |
Revision as of 06:29, 5 March 2015
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Definition
Identifies a gene or gene product affected by a regulation Biological Process or regulator Molecular Function.
Child terms
- None
Scope of use
Domain
GO:0065007 ! biological regulation
Range
ENTITY_UNION:0000005 ! chemical, gene product or complex
Annotation Extension Usage Examples
Loss of transcription factor activity affects gene expression:
Statements from paper:
Indeed, LGG-1 was massively upregulated in atf-2(tm467) mutant embryos, as compared with the wild type (Fig. 6A). We observed a similar extent of BEC-1 upregulation in the atf-2-deficient background (data not shown).
Gene Name (col 2) | GO ID (col 5) | Reference (col 6) | Evidence (col 7) | Annotation Extension (col 16) |
---|---|---|---|---|
WBGene00000220 atf-2(tm467) | GO:0000122 negative regulation of transcription from RNA polymerase II promoter | PMID:21502138 | IMP | has_regulation_target(WB:WBGene00002980 lgg-1 |
Using examples (from above) to demonstrate Folding_and_Unfolding using the relationship has_regulation_target
Specifying the gene which is a target of a transcription factor
gene transcription targets
Statement example:
DNA binding transcription factor A binds the promoter of Polo2 and increases transcription of Polo2
Folded/unfolded | Gene Name (col 2) | GO ID (col 5) | Reference (col 6) | Evidence (col 7) | Annotation Extension (col 16) | Parent terms of new folded GO term |
---|---|---|---|---|---|---|
Unfolded | WBGene00000220 atf-2(tm467) | GO:0000122 negative regulation of transcription from RNA polymerase II promoter | PMID:21502138 | IMP | has_regulation_target(WB:WBGene00002980 lgg-1 | |
Folded | WBGene00000220 atf-2(tm467) | GO:0000122 negative regulation of transcription from RNA polymerase II promoter | PMID:21502138 | IMP | No new GO term created |
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Back to Annotation usage examples for each annotation extension relation