Has small molecular inhibitor: Difference between revisions
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'''OWL class expression:''' GO: 0004072 <font color = "red">aspartate kinase activity</font> is inhibited_by some CHEBI: 16857 <font color = "red">L-threonine </font> | '''OWL class expression:''' GO: 0004072 <font color = "red">aspartate kinase activity</font> is inhibited_by some CHEBI: 16857 <font color = "red">L-threonine </font> | ||
{| class="wikitable" border="1" | |||
! Folded/unfolded | |||
!Object (Col 2) | |||
!GO ID (Col 5) | |||
!Reference (Col 6) | |||
!Evidence | |||
!Extension (Col 16) | |||
!Parent terms for new folded GO term | |||
|- | |||
| Unfolded | |||
| P32783, <font color = "green">ABD1</font> | |||
| GO:0004482, <font color = "green">mRNA (guanine-N7-)-methyltransferase activity</font> | |||
| PMID: 7623811 | |||
| IDA | |||
|inhibited_by: CHEBI:16680 <font color = "green">S-adenosyl-L-homocysteine</font> | |||
| | |||
|- | |||
| folded | |||
| P32783, <font color = "green">ABD1</font> | |||
| | |||
| PMID: 7623811 | |||
| IDA | |||
| | |||
| | |||
|- | |||
|} | |||
---- | ---- |
Revision as of 18:42, 26 February 2015
Back to Annotation usage examples for each annotation extension relation
Definition
Identifies a chemical substance that decreases the activity of the gene product.
Comment
This relation should not be used to annotate one gene product regulating another's activity; a regulator Molecular Function or regulation Biological Process should be used in such cases.
Synonyms
activity_decreased_by (EXACT)
inhibited_by_chemical (EXACT)
inhibited_by_substance (EXACT)
Child terms
- None.
Scope of use
Domain
GO:0003674 ! molecular_function
Range
CHEBI:24431 ! chemical entity
Annotation Extension Usage Examples
Gene Name (col 2) | GO ID (col 5) | Reference (col 6) | Evidence (col 7) | With (col 8) | Annotation Extension (col 16) |
---|---|---|---|---|---|
P10869, HOM3 | GO:0004072 aspartate kinase activity | PMID:18626862 | IDA | inhibited_by: CHEBI:16857L-threonine | |
P32783, ABD1 | GO:0004482, mRNA (guanine-N7-)-methyltransferase activity | PMID: 7623811 | IDA | inhibited_by: CHEBI:16680 S-adenosyl-L-homocysteine |
Using examples to demonstrate Folding_and_Unfolding using the relationship inhibited_by
Folded/unfolded | Object (Col 2) | GO ID (Col 5) | Reference (Col 6) | Evidence | Extension (Col 16) | Parent terms for new folded GO term |
---|---|---|---|---|---|---|
Unfolded | P10869, HOM3 | GO:0004072 aspartate kinase activity | PMID:18626862 | IDA | inhibited_by: CHEBI:16857L-threonine | |
Folded | P10869, HOM3 | ?? | PMID:18626862 | IDA |
OWL class expression: GO: 0004072 aspartate kinase activity is inhibited_by some CHEBI: 16857 L-threonine
Folded/unfolded | Object (Col 2) | GO ID (Col 5) | Reference (Col 6) | Evidence | Extension (Col 16) | Parent terms for new folded GO term |
---|---|---|---|---|---|---|
Unfolded | P32783, ABD1 | GO:0004482, mRNA (guanine-N7-)-methyltransferase activity | PMID: 7623811 | IDA | inhibited_by: CHEBI:16680 S-adenosyl-L-homocysteine | |
folded | P32783, ABD1 | PMID: 7623811 | IDA |
Back to Annotation usage examples for each annotation extension relation