Has small molecular inhibitor: Difference between revisions
Line 74: | Line 74: | ||
| PMID:18626862 | | PMID:18626862 | ||
| IDA | | IDA | ||
|inhibited_by: CHEBI:16857<font color = "green">L-threonine </font> | | inhibited_by: CHEBI:16857<font color = "green">L-threonine </font> | ||
| | | | ||
|- | |- | ||
| Folded | | Folded | ||
| P10869, <font color = "green">HOM3</font> | | P10869, <font color = "green">HOM3</font> | ||
| | | GO:0004072 <font color = "green">aspartate kinase activity</font> | ||
|PMID:18626862 | | PMID:18626862 | ||
|IDA | | IDA | ||
| | | | ||
| <span style="color:red">No new GO term created</span> | |||
|- | |- | ||
|} | |} | ||
Line 104: | Line 104: | ||
| PMID: 7623811 | | PMID: 7623811 | ||
| IDA | | IDA | ||
|inhibited_by: CHEBI:16680 <font color = "green">S-adenosyl-L-homocysteine</font> | | inhibited_by: CHEBI:16680 <font color = "green">S-adenosyl-L-homocysteine</font> | ||
| | | | ||
|- | |- | ||
| folded | | folded | ||
| P32783, <font color = "green">ABD1</font> | | P32783, <font color = "green">ABD1</font> | ||
| | | GO:0004482, <font color = "green">mRNA (guanine-N7-)-methyltransferase activity</font> | ||
| PMID: 7623811 | | PMID: 7623811 | ||
| IDA | | IDA | ||
| | | | ||
| | | <span style="color:red">No new GO term created</span> | ||
|- | |- | ||
|} | |} |
Revision as of 07:07, 5 March 2015
Back to Annotation usage examples for each annotation extension relation
Definition
Identifies a chemical substance that decreases the activity of the gene product.
Comment
This relation should not be used to annotate one gene product regulating another's activity; a regulator Molecular Function or regulation Biological Process should be used in such cases.
Synonyms
activity_decreased_by (EXACT)
inhibited_by_chemical (EXACT)
inhibited_by_substance (EXACT)
Child terms
- None.
Scope of use
Domain
GO:0003674 ! molecular_function
Range
CHEBI:24431 ! chemical entity
Annotation Extension Usage Examples
Gene Name (col 2) | GO ID (col 5) | Reference (col 6) | Evidence (col 7) | With (col 8) | Annotation Extension (col 16) |
---|---|---|---|---|---|
P10869, HOM3 | GO:0004072 aspartate kinase activity | PMID:18626862 | IDA | inhibited_by: CHEBI:16857L-threonine | |
P32783, ABD1 | GO:0004482, mRNA (guanine-N7-)-methyltransferase activity | PMID: 7623811 | IDA | inhibited_by: CHEBI:16680 S-adenosyl-L-homocysteine |
Using examples to demonstrate Folding_and_Unfolding using the relationship inhibited_by
Folded/unfolded | Object (Col 2) | GO ID (Col 5) | Reference (Col 6) | Evidence | Extension (Col 16) | Parent terms for new folded GO term |
---|---|---|---|---|---|---|
Unfolded | P10869, HOM3 | GO:0004072 aspartate kinase activity | PMID:18626862 | IDA | inhibited_by: CHEBI:16857L-threonine | |
Folded | P10869, HOM3 | GO:0004072 aspartate kinase activity | PMID:18626862 | IDA | No new GO term created |
OWL class expression: GO: 0004072 aspartate kinase activity is inhibited_by SOME CHEBI: 16857 L-threonine
Folded/unfolded | Object (Col 2) | GO ID (Col 5) | Reference (Col 6) | Evidence | Extension (Col 16) | Parent terms for new folded GO term |
---|---|---|---|---|---|---|
Unfolded | P32783, ABD1 | GO:0004482, mRNA (guanine-N7-)-methyltransferase activity | PMID: 7623811 | IDA | inhibited_by: CHEBI:16680 S-adenosyl-L-homocysteine | |
folded | P32783, ABD1 | GO:0004482, mRNA (guanine-N7-)-methyltransferase activity | PMID: 7623811 | IDA | No new GO term created |
OWL class expression: GO: 0004482, mRNA (guanine-N7-)-methyltransferase activity is inhibited_by SOME CHEBI:16680 S-adenosyl-L-homocysteine
Back to Annotation usage examples for each annotation extension relation