Annotation Extension Relation:requires regulator: Difference between revisions

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==Definition==
#REDIRECT [[Annotation]] 


The annotated gene product requires regulation by the gene product or complex for its participation in the Molecular Function or Biological Process.
'''THIS RELATION IS DEPRECATED'''


==Child terms==
<pre style="color:#808080">


* None.
==Annotation Extension Usage Examples==
 
'''Direct Activation of Bax by p53 Mediates Mitochondrial Membrane Permeabilization and Apoptosis'''
 
Statement from paper: 
 
''...we examined the effect of p53 on isolated mitochondria with and without Bax. Neither recombinant monomeric Bax nor native p53UVIP induced cytochrome c release on its own; however, incubation of mitochondria with both proteins caused cytochrome c release (Fig. 2B).'' 


==Scope of use==


===Domain===


BFO:0000007 ! Biological Process or Molecular Function
{| class="wikitable" border="1"
|-
! Gene Name (col 2)
! GO ID (col 5)
! Reference (col 6)
! Evidence (col 7)
! Annotation Extension (col 16)
|-
| Q07812
|GO:0090200 <span style="color:green">positive regulation of release of cytochrome c from mitochondria</span>
| PMID:14963330
| IDA
|
requires_regulator(UniProtKB:P04637 <span style="color:green">p53</span>)
|}


===Range===


[[ENTITY_UNION:0000001]] ! gene product or complex


==Annotation Extension Usage Examples==
 
----
</pre>




Back to [http://wiki.geneontology.org/index.php/Annotation_usage_examples_for_each_annotation_extension_relation Annotation usage examples for each annotation extension relation]
Back to [http://wiki.geneontology.org/index.php/Annotation_usage_examples_for_each_annotation_extension_relation Annotation usage examples for each annotation extension relation]


[[Category:relations]]
[[Category:Deprecated]]
[[Category:annotation extension]]

Latest revision as of 08:18, 27 September 2021

Redirect to:

 

THIS RELATION IS DEPRECATED

 

==Annotation Extension Usage Examples==

'''Direct Activation of Bax by p53 Mediates Mitochondrial Membrane Permeabilization and Apoptosis'''

Statement from paper:  

''...we examined the effect of p53 on isolated mitochondria with and without Bax. Neither recombinant monomeric Bax nor native p53UVIP induced cytochrome c release on its own; however, incubation of mitochondria with both proteins caused cytochrome c release (Fig. 2B).''  



{| class="wikitable" border="1"
|-
! Gene Name (col 2)
! GO ID (col 5)
! Reference (col 6)
! Evidence (col 7)
! Annotation Extension (col 16)
|-
| Q07812
|GO:0090200 <span style="color:green">positive regulation of release of cytochrome c from mitochondria</span>
| PMID:14963330
| IDA
| 
requires_regulator(UniProtKB:P04637 <span style="color:green">p53</span>)
|}




----


Back to Annotation usage examples for each annotation extension relation