Annotation Extension Relation:results in division of: Difference between revisions
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Back to [http://wiki.geneontology.org/index.php/Annotation_usage_examples_for_each_annotation_extension_relation Annotation usage examples for each annotation extension relation] | |||
==Definition== | ==Definition== | ||
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==Annotation Extension Usage Examples== | ==Annotation Extension Usage Examples== | ||
1. Gata3 is required for reactive proliferation of radial glial cells | '''1. Gata3 is required for reactive proliferation of radial glial cells in telencephalon of adult zebrafish''' | ||
Paper: "Regenerative Neurogenesis from Neural Progenitor Cells Requires Injury-Induced Expression of Gata3" (PMID: 23168169) | Paper: "Regenerative Neurogenesis from Neural Progenitor Cells Requires Injury-Induced Expression of Gata3" (PMID: 23168169) | ||
Statement from paper: | Statement from paper: | ||
''"... knocking down gata3 reduces the number of injury-stimulated proliferation [of radial glial cells] at 3pdl significantly, to the level characteristic for unlesioned telencephalon."'' | |||
{| class="wikitable" border="1" | |||
|- | |||
! | |||
! Gene Name (col 2) | |||
! GO ID (col 5) | |||
! Reference (col 6) | |||
! Evidence (col 7) | |||
! Annotation Extension (col 16) | |||
! Parent terms of new folded GO term | |||
|- | |||
| Unfolded | |||
| Q91428 Gata3 | |||
| GO:0008284 positive regulation of cell proliferation | |||
| PMID: 23168169 | |||
| IMP | |||
| results_in_division_of (CL:0013000 forebrain radial glial cell) | |||
|- | |||
| Folded | |||
| Q91428 Gata3 | |||
| New GO ID positive regulation of forebrain radial glial cell proliferation | |||
| PMID: 23168169 | |||
| IMP | |||
| | |||
| is_a new GO: positive regulation of radial glial cell proliferation, is_a child of GO:0008284 positive regulation of cell proliferation | |||
|} | |||
'''OWL class expression:''' GO:0008284 <span style="color:red">positive regulation of cell proliferation</span> results_in_division_of SOME CL:0013000 <span style="color:red">forebrain radial glial cell</span> | |||
'''2. Pax6a and Pax6b are required during neuronal progenitor proliferation in retina of adult zebrafish''' | |||
Paper: "Pa6a and Paxb are required at different points in neuronal progenitor cell proliferation during zebrafish photoreceptor regeneration" (PMID: 20152834) | |||
Statement from paper: | |||
''"...knockdown of Pax6b expression inhibited the subsequent division of the Müller glia-derived INL neuronal progenitor. In contrast, reduction of Pax6a expression allowed this initial neuronal progenitor cell division, but it prevented later cell divisions."'' | |||
{| class="wikitable" border="1" | |||
|- | |||
! | |||
! Gene Name (col 2) | |||
! GO ID (col 5) | |||
! Reference (col 6) | |||
! Evidence (col 7) | |||
! Annotation Extension (col 16) | |||
! Parent terms of new folded GO term | |||
|- | |||
| Unfolded | |||
| P26630 Pax6a | |||
| GO:0008284 positive regulation of cell proliferation | |||
| PMID: 20152834 | |||
| IMP | |||
| results_in_division_of (CL:0002672 retinal progenitor cell) | |||
|- | |||
| Folded | |||
| P26630 Pax6a | |||
| New GO ID positive regulation of retinal progenitor cell proliferation | |||
| PMID: 20152834 | |||
| IMP | |||
| | |||
| is_a GO:0008284 positive regulation of cell proliferation | |||
|} | |||
'''OWL class expression:''' GO:0008284 <span style="color:red">positive regulation of cell proliferation</span> results_in_division_of SOME CL:0002672 <span style="color:red">retinal progenitor cell</span> | |||
{| class="wikitable" border="1" | {| class="wikitable" border="1" | ||
|- | |- | ||
! Gene Name (col 2) | ! | ||
! GO ID (col 5) | ! Gene Name (col 2) | ||
! Reference (col 6) | ! GO ID (col 5) | ||
! Evidence (col 7) | ! Reference (col 6) | ||
! Annotation Extension (col 16) | ! Evidence (col 7) | ||
! Annotation Extension (col 16) | |||
! Parent terms of new folded GO term | |||
|- | |||
| Unfolded | |||
| Q6DHA8 Pax6b | |||
| GO:0008284 positive regulation of cell proliferation | |||
| PMID: 20152834 | |||
| IMP | |||
| results_in_division_of (CL:0002672 retinal progenitor cell) | |||
|- | |- | ||
| | | Folded | ||
| | | Q6DHA8 Pax6b | ||
| | | New GO ID positive regulation of retinal progenitor cell proliferation | ||
| | | PMID: 20152834 | ||
| | | IMP | ||
| | |||
| is_a GO:0008284 positive regulation of cell proliferation | |||
|} | |} | ||
'''OWL class expression:''' GO:0008284 <span style="color:red">positive regulation of cell proliferation</span> results_in_division_of SOME CL:0002672 <span style="color:red">retinal progenitor cell</span> | |||
---- | ---- |
Latest revision as of 07:43, 5 March 2015
Back to Annotation usage examples for each annotation extension relation
Definition
The relationship linking a entity and its participation in a process that results in the division of the entity into two entities of the same type.
Comment
Example of use: an annotation of gene X to cell division with results_in_division_of CL:0000057 (fibroblast) means that at the end of the process a single fibroblast has divided into two fibroblasts.
Child terms
- None.
Scope of use
Domain
GO:0003674 (molecular_function) or GO:0008150 (biological_process)
Range
CL:0000000 (cell) or WBbt:0004017 (cell)
Annotation Extension Usage Examples
1. Gata3 is required for reactive proliferation of radial glial cells in telencephalon of adult zebrafish
Paper: "Regenerative Neurogenesis from Neural Progenitor Cells Requires Injury-Induced Expression of Gata3" (PMID: 23168169)
Statement from paper: "... knocking down gata3 reduces the number of injury-stimulated proliferation [of radial glial cells] at 3pdl significantly, to the level characteristic for unlesioned telencephalon."
Gene Name (col 2) | GO ID (col 5) | Reference (col 6) | Evidence (col 7) | Annotation Extension (col 16) | Parent terms of new folded GO term | |
---|---|---|---|---|---|---|
Unfolded | Q91428 Gata3 | GO:0008284 positive regulation of cell proliferation | PMID: 23168169 | IMP | results_in_division_of (CL:0013000 forebrain radial glial cell) | |
Folded | Q91428 Gata3 | New GO ID positive regulation of forebrain radial glial cell proliferation | PMID: 23168169 | IMP | is_a new GO: positive regulation of radial glial cell proliferation, is_a child of GO:0008284 positive regulation of cell proliferation |
OWL class expression: GO:0008284 positive regulation of cell proliferation results_in_division_of SOME CL:0013000 forebrain radial glial cell
2. Pax6a and Pax6b are required during neuronal progenitor proliferation in retina of adult zebrafish
Paper: "Pa6a and Paxb are required at different points in neuronal progenitor cell proliferation during zebrafish photoreceptor regeneration" (PMID: 20152834)
Statement from paper: "...knockdown of Pax6b expression inhibited the subsequent division of the Müller glia-derived INL neuronal progenitor. In contrast, reduction of Pax6a expression allowed this initial neuronal progenitor cell division, but it prevented later cell divisions."
Gene Name (col 2) | GO ID (col 5) | Reference (col 6) | Evidence (col 7) | Annotation Extension (col 16) | Parent terms of new folded GO term | |
---|---|---|---|---|---|---|
Unfolded | P26630 Pax6a | GO:0008284 positive regulation of cell proliferation | PMID: 20152834 | IMP | results_in_division_of (CL:0002672 retinal progenitor cell) | |
Folded | P26630 Pax6a | New GO ID positive regulation of retinal progenitor cell proliferation | PMID: 20152834 | IMP | is_a GO:0008284 positive regulation of cell proliferation |
OWL class expression: GO:0008284 positive regulation of cell proliferation results_in_division_of SOME CL:0002672 retinal progenitor cell
Gene Name (col 2) | GO ID (col 5) | Reference (col 6) | Evidence (col 7) | Annotation Extension (col 16) | Parent terms of new folded GO term | |
---|---|---|---|---|---|---|
Unfolded | Q6DHA8 Pax6b | GO:0008284 positive regulation of cell proliferation | PMID: 20152834 | IMP | results_in_division_of (CL:0002672 retinal progenitor cell) | |
Folded | Q6DHA8 Pax6b | New GO ID positive regulation of retinal progenitor cell proliferation | PMID: 20152834 | IMP | is_a GO:0008284 positive regulation of cell proliferation |
OWL class expression: GO:0008284 positive regulation of cell proliferation results_in_division_of SOME CL:0002672 retinal progenitor cell
Back to Annotation usage examples for each annotation extension relation