Annotation Extension Relation:results in division of
Definition
The relationship linking a entity and its participation in a process that results in the division of the entity into two entities of the same type.
Comment
Example of use: an annotation of gene X to cell division with results_in_division_of CL:0000057 (fibroblast) means that at the end of the process a single fibroblast has divided into two fibroblasts.
Child terms
- None.
Scope of use
Domain
GO:0003674 (molecular_function) or GO:0008150 (biological_process)
Range
CL:0000000 (cell) or WBbt:0004017 (cell)
Annotation Extension Usage Examples
1. Gata3 is required for reactive proliferation of radial glial cells in telencephalon of adult zebrafish
Paper: "Regenerative Neurogenesis from Neural Progenitor Cells Requires Injury-Induced Expression of Gata3" (PMID: 23168169)
Statement from paper: "... knocking down gata3 reduces the number of injury-stimulated proliferation [of radial glial cells] at 3pdl significantly, to the level characteristic for unlesioned telencephalon."
| Gene Name (col 2) | GO ID (col 5) | Reference (col 6) | Evidence (col 7) | Annotation Extension (col 16) | Parent terms of new folded GO term | |
|---|---|---|---|---|---|---|
| Unfolded | Q91428 Gata3 | GO:0008284 positive regulation of cell proliferation | PMID: 23168169 | IMP | results_in_division_of (CL:0013000 forebrain radial glial cell) | |
| Folded | Q91428 Gata3 | New GO ID positive regulation of forebrain radial glial cell proliferation | PMID: 23168169 | IMP | is_a GO: positive regulation of radial glial cell proliferation, child of GO:0008284 positive regulation of cell proliferation |
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