Annotation Extension Relation:results in specification of: Difference between revisions
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| PMID:19427847 | | PMID:19427847 | ||
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| WB:WBVar00091938 | | WB:WBVar00091938 | ||
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| is_a <span style="color:red">mesodermal cell fate specification</span> | | is_a <span style="color:red">mesodermal cell fate specification</span> | ||
|- | |- |
Revision as of 10:45, 6 March 2015
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Definition
The relationship linking a cell and its participation in a Molecular Function or Biological Process that results in the fate of the cell being specified. Once specification has taken place, a cell will be committed to differentiate down a specific pathway if left in its normal environment.
Comment
Synonyms
Child terms
- None
Scope of use
Domain
BFO:0000007 ! process (Biological Process or Molecular Function)
Range
CL:0000000 ! cell
Annotation Extension Usage Examples
Indicating the cell or cell type specified by the activity of a gene product
Statement from paper:
However, the strong loss-of-function allele of eya-1, ok654 (Furuya et al., 2005), displayed M lineage phenotypes similar to ceh-34(RNAi-P): loss of M-derived CCs and variable loss of embryonic CCs (Table 1, Fig. 3A). Thus, both ceh-34 and eya-1 are required for specifying the embryonic and M-derived CCs.
Note that in the above sentence, M refers to the M mesoblast and CCs refers to coelomocytes.
Gene Name (col 2) | GO ID (col 5) | Reference (col 6) | Evidence (col 7) | With (col 8) | Annotation Extension (col 16) |
---|---|---|---|---|---|
Q94165 ceh-34 | GO:0007501 mesodermal cell fate specification | PMID:19427847 | IMP | WB:WBRNAi00101780 | results_in_specification_of(WBbt:0005751 coelomocyte) |
O17670 eya-1 | GO:0007501 mesodermal cell fate specification | PMID:19427847 | IMP | WB:WBVar00091938 | results_in_specification_of(WBbt:0005751 coelomocyte) |
Using examples to demonstrate Folding_and_Unfolding using the relationship results_in_specification_of
Indicating the cell or cell type specified by the activity of a gene product
Statement from paper:
However, the strong loss-of-function allele of eya-1, ok654 (Furuya et al., 2005), displayed M lineage phenotypes similar to ceh-34(RNAi-P): loss of M-derived CCs and variable loss of embryonic CCs (Table 1, Fig. 3A). Thus, both ceh-34 and eya-1 are required for specifying the embryonic and M-derived CCs.
Folded/unfolded | Gene Name (col 2) | GO ID (col 5) | Reference (col 6) | Evidence (col 7) | With (col 8) | Annotation Extension (col 16) | Parent terms of new folded GO term |
---|---|---|---|---|---|---|---|
Unfolded | Q94165 ceh-34 | GO:0007501 mesodermal cell fate specification | PMID:19427847 | IMP | WB:WBRNAi00101780 | results_in_specification_of(WBbt:0005751 coelomocyte) | |
Unfolded | O17670 eya-1 | GO:0007501 mesodermal cell fate specification | PMID:19427847 | IMP | WB:WBVar00091938 | results_in_specification_of(WBbt:0005751 coelomocyte) | |
Folded | Q94165 ceh-34 | GO:0007501 mesodermal cell fate specification resulting in specification of coelomocyte | PMID:19427847 | IMP | WB:WBRNAi00101780 | is_a mesodermal cell fate specification | |
Folded | O17670 eya-1 | GO:0007501 mesodermal cell fate specification resulting in specification of coelomocyte | PMID:19427847 | IMP | WB:WBVar00091938 | is_a mesodermal cell fate specification |
OWL class expression:
OWL class expression: GO:0007501 mesodermal cell fate specification results_in_specification_of SOME WBbt:0005751 coelomocyte
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