Annotation camp report

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GO Annotation Camp

The 3rd GO Annotation Camp was held at Stanford University on July 10-14 2006. During the first two days members of the GO consortium met to discuss annotation standards, focusing on the consistent use of evidence codes. During the discussion we were able to clarify usage guidelines for cases in which multiple evidences codes could be used to support a GO annotation (e.g.a protein binding experiment may be annotated with IDA (Inferred by Direct Assay) or IPI (Inferred by Physical Interaction) evidence codes. In addition, we agreed to refine the use of certain codes or extend the use of other codes in light of new experimental approaches. All of the recommendations will be incorporated into revised evidence code documentation (http://www.geneontology.org/GO.evidence.shtml) that will clarify the use of codes for new groups and should improve annotation consistency between current groups.

The second part of the meeting was devoted to training 30 curators how to manually curate GO annotations from literature. These curators represented a diverse mix of plant, animal, fungal and bacterial databases. The training included presentations about the onotologies, the evidence codes and the process of annotation, by GO consortium members as well as the opportunity to gain practical experience by annotating a representative set of ten publications in small groups guided by an experienced GO curator. This set of reference papers, annotated under the new guidelines, represents a valuable training resource that will be available on the GO web site.

Thanks to Incyte and the Department of Genetics at the School of Medicine, Stanford University for supporting this meeting.If you are interested in attending next year's annotation camp, please contact gohelp@genome.stanford.edu.

Newsletter 2nd edition