Cardiac conduction: fish vs. mammals: Difference between revisions
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# next, a significant AV conduction delay develops during cardiac chamber formation (36–48 hpf) | # next, a significant AV conduction delay develops during cardiac chamber formation (36–48 hpf) | ||
# as the heart loops and develops ventricular trabeculations (72–96 hpf), an immature fast conduction network develops within the ventricle | # as the heart loops and develops ventricular trabeculations (72–96 hpf), an immature fast conduction network develops within the ventricle | ||
#finally, this fast conduction network fully matures to an | #finally, this fast conduction network fully matures to an apex-to-base activation pattern when the ventricular apex has | ||
formed. | formed. | ||
Revision as of 16:59, 17 June 2011
Back to: cardiac conduction
Birds:
Many avian species develop an AV-ring which plays a role similar to that of the mammalian AV-node (Szabo et al. Anat Rec. 1986 May;215(1):1-9. PubMed PMID:3706789.) [[1]]
Steps in CCS develoment in zebrafish:
From Genetic and physiologic dissection of the vertebrate cardiac conduction system. PLoS Biol. 2008 May 13;6(5):e109. PubMed PMID: 18479184; PubMed Central PMCID: PMC2430899. [[2]]
- Initially, a linear conduction travels across the heart tube from the sinus venosus to the OFT (20–24 hours postfertilization (hpf)).
- next, a significant AV conduction delay develops during cardiac chamber formation (36–48 hpf)
- as the heart loops and develops ventricular trabeculations (72–96 hpf), an immature fast conduction network develops within the ventricle
- finally, this fast conduction network fully matures to an apex-to-base activation pattern when the ventricular apex has
formed.