Causally upstream of, negative effect: Difference between revisions

From GO Wiki
Jump to navigation Jump to search
Line 1: Line 1:
== Overview and Scope of Use==
== Overview and Scope of Use==
*This relation is used in GO-CAMs but not in standard annotation extensions.
*This relation is used in GO-CAMs but not in standard annotation extensions.
* This relation is intended to represent a negative causal effect of on activity on another, where the mechanism is not known.
* This relation is intended to represent a negative causal effect of one activity on another, where the mechanism is not known.
*The 'causally upstream of, negative effect' relation is used to relate two GO Molecular Functions when:
*The 'causally upstream of, negative effect' relation is used to relate two GO Molecular Functions when:
**the mechanism that relates the upstream molecular function to the downstream molecular function is not understood
**the mechanism that relates the upstream molecular function to the downstream molecular function is not understood

Revision as of 09:18, 8 February 2023

Overview and Scope of Use

  • This relation is used in GO-CAMs but not in standard annotation extensions.
  • This relation is intended to represent a negative causal effect of one activity on another, where the mechanism is not known.
  • The 'causally upstream of, negative effect' relation is used to relate two GO Molecular Functions when:
    • the mechanism that relates the upstream molecular function to the downstream molecular function is not understood
    • the upstream molecular function occurs before the downstream molecular function
    • the upstream molecular function has a negative effect on the downstream molecular function

Annotation Usage Guidelines

  • What to capture
    • Relationships between molecular functions when a negative effect has been demonstrated but the mechanism is not known.
  • What not to capture
    • Relationships where the mechanism is known. These should be represented by other relationships.

Examples

  • TBD

Ontology Usage Guidelines

This relation is not used in the ontology.

Relations Ontology

causally upstream of, negative effect

Review Status

Last reviewed: October 31, 2022 David

Back to: Annotation Relations