Causally upstream of, negative effect: Difference between revisions
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== Overview and Scope of Use== | == Overview and Scope of Use== | ||
*This relation is used in GO-CAMs but not in standard annotation extensions. | *This relation is used in GO-CAMs but not in standard annotation extensions. | ||
* This relation is intended to represent a negative causal effect of | * This relation is intended to represent a negative causal effect of one activity on another, where the mechanism is not known. | ||
*The 'causally upstream of, negative effect' relation is used to relate two GO Molecular Functions when: | *The 'causally upstream of, negative effect' relation is used to relate two GO Molecular Functions when: | ||
**the mechanism that relates the upstream molecular function to the downstream molecular function is not understood | **the mechanism that relates the upstream molecular function to the downstream molecular function is not understood |
Revision as of 09:18, 8 February 2023
Overview and Scope of Use
- This relation is used in GO-CAMs but not in standard annotation extensions.
- This relation is intended to represent a negative causal effect of one activity on another, where the mechanism is not known.
- The 'causally upstream of, negative effect' relation is used to relate two GO Molecular Functions when:
- the mechanism that relates the upstream molecular function to the downstream molecular function is not understood
- the upstream molecular function occurs before the downstream molecular function
- the upstream molecular function has a negative effect on the downstream molecular function
Annotation Usage Guidelines
- What to capture
- Relationships between molecular functions when a negative effect has been demonstrated but the mechanism is not known.
- What not to capture
- Relationships where the mechanism is known. These should be represented by other relationships.
Examples
- TBD
Ontology Usage Guidelines
This relation is not used in the ontology.
Relations Ontology
causally upstream of, negative effect
Review Status
Last reviewed: October 31, 2022 David